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生物活性分子最近更新
含乙二醛酶结构域 4（GLOD4）基因
Alpl
Asymmetric Total Syntheses of Kopsia Indole Alkaloids PMID 28230294
o
α
L
6
9,10,16
PFP@PLGA/Cu12Sb4S13
CRBN ligand
Set
The action of ranatensin, a new polypeptide from amphibian skin, on the blood pressure of experimental animals PMID 4322040
CCL2
CD166/ALCAM expression is characteristic of tumorigenicity and invasive and migratory activities of pancreatic cancer cells PMID 25221999
ZIMET 124/73
Antituberculosis agent
Phospholipase C 蛋白, Bacillus cereus
Mannose 1
Antiproliferative agent
3
G
Enhancement of nitrocaphane cytotoxicity by hyperthermia in vitro PMID 2746055
Cis
Malic Dehydrogenase, Bovine
Nitrocaphane
trans
STAT6 modulator
bacteriophages
Phaseic acid 24394
RRH
[Effect of riodoxol on herpes simplex virus morphogenesis in experimental eye infection] PMID 6280397
Avellanin B 110297
HSMO9
STAT6 modulator
Ears2 Mouse Pre
Inhibiting Hedgehog An Update on Pharmacological Compounds and Targeting Strategies PMID 30986059
2
Il17rd Mouse Pre
Nitrocaphane 54940
Role of GABAA and GABAC receptors in the biphasic GABA responses in neurons of the rat major pelvic ganglia PMID 10482764
Famotidine impurity 7 129083
bacterial viruses
Proteasefrom aspergillus oryzae 9074
A structure
RO7
OLFML3 Human Pre
8,9
[Combined treatment of malignant trophoblastic tumor with 5
ITPR2 Human Pre
Penetratin
Cinitapride protects against ethanol
deoxidizer
HCV Peptide (257
EHD2 Human Pre
Boc
ITPKC Human Pre
GSK
PC Linker phosphoramidite
MCE
Octadecan
H
cAMP 反应元件结合蛋白 5（CREB5）基因
MINDY 赖氨酸 48 去泛素化酶 2（MINDY2）基因
推定的同源域转录因子 2（PHTF2）基因
核 GTPase，生发中心相关（NUGGC）基因
整合复合物亚基 14（INTS14）基因
中线 2（MID2）基因
精子尾部外层致密纤维 2（ODF2）基因
甘露糖
左右决定因素 1（LEFTY1）基因
线粒体核糖体蛋白 L3（MRPL3）基因
富亮氨酸重复 LGI 家族成员 2（LGI2）基因
含核苷酸结合寡聚化结构域 2（Nod2）基因
含 LIM 锌指结构域 2（LIMS2）基因
整合复合物亚基 10（INTS10）基因
NOVA 可变剪接调节器 1（NOVA1）基因
配对样同源域 3（PITX3）基因
动力蛋白轴丝重链 6（DNAH6）基因
干扰素调节因子 2 结合蛋白样（IRF2BPL）基因
mutS 同系物 2（MSH2）基因
MORC 家族 CW 型锌指 2（MORC2）基因
腈水解酶 1（NIT1）基因
α
LLGL scribble 细胞极性复数组分 2（LLGL2）基因
LIM 域绑定 3（LDB3）基因
嗅觉调节素 2（OLFM2）基因
钙粘蛋白 9（CDH9）基因
Proteoglycans Enhance the Therapeutic Effect of BMSC Transplantation on Osteoarthritis PMID 39593826
5'
neonates
Scientific opinion on flavouring group evaluation 77, revision 3 (FGE.77Rev3) consideration of pyridine, pyrrole and quinoline derivatives evaluated by JECFA (63rd meeting) structurally related to pyridine, pyrrole, indole and quinoline derivatives evaluated by EFSA in FGE.24Rev2 PMID 32625865
HSMO
Pneumocandin A2 135867
Cianopramine hydrochloride 66834
A new mechanism of inhibition of IL
RPR106541
MCE
NPY1R
Porcupine
E138
PROTAC
NCoA
Bis
GalNAc
Abscisic acid Sterile Solution (1 mg/ml) (脱落酸无菌溶液 (1 mg/ml))
MAGEA2 Human Pre
Antibiotic compounds with action against bacterial viruses neohydroxyaspergillic acid PMID 13522233
Organic additives stabilize RNA aptamer binding of malachite green PMID 27591602
Aldehyde dehydrogenase 18
NEURL2 Human Pre
Cell targeting peptide conjugation to siRNA polyplexes for effective gene silencing in cardiomyocytes PMID 22452378
P2ry2 Mouse Pre
A 2
SOS1 Ligand intermediate
[BMIM]Cl 79917
PASD1 Human Pre
可的唑
BAT6005
Design and synthesis of novel ATP
Famotidine impurity 2 124646
DBCO
Tris(4
SAK
OCEL1 Human Pre
KHDC4 Human Pre
牛漆姑提取物 (Spergularia marina (L.) Griseb.)
NETO2 Human Pre
HCV Peptide (131
LM
Hydroxyzine
m
Lpar5 Mouse Pre
PDHA2 Human Pre
Mgat2 Mouse Pre
PHLDB1 Human Pre
At
pdU
Planchol E 1346137
ODC1 Human Pre
Targeting the lymphotoxin
LIM2 Human Pre
Limonoids from the roots of Trichilia sinensis and their cytotoxicities PMID 29170993
C.I. Pigment orange 36
Glu166
ITIH2 Human Pre
AMD
HAND1 抗体（HAND1 Antibody）
islet
Vesleteplirsen sodium (SRP
Novel quinone methides from Salacia kraussii with in vitro antimalarial activity PMID 9644053
double
Alverine citrate 5560
FGL1 蛋白, Human (Biotinylated, 242a.a, HEK293, His
Synthesis and antitumor activities of novel 6
CP
Identification of a novel HIV
LYPD2 Human Pre
Hedgehog
SHKBP1 Human Pre
KRT4 Human Pre
Effects of butachlor on reproduction and hormone levels in adult zebrafish (Danio rerio) PMID 21920721
Safety evaluation of the food enzyme oryzin from the non
TRAPPC2 Human Pre
MRS2 Human Pre
Assessment of human pregnane X receptor involvement in pesticide
Bis
FK 565
PD
INSA 2962939
IM
Nociceptin 170713
Identification of new inhibitors of protein kinase R guided by statistical modeling PMID 21632247
ADM2
TryR
MEST
MOS
In vitro and in vivo antischistosomal activity of ferroquine derivatives PMID 25190030
Dco
Cinitapride
(12Z,15Z,18Z,21Z)
Coumarins from campylotropis hirtella (FRANCH.) SCHINDL. and their inhibitory activity on prostate specific antigen secreted from LNCaP cells PMID 18758115
PTP1B
Antibiotics in experimental cancer chemotherapy PMID 13920161
Effect of testosterone suppression on the pharmacokinetics of a potent gnRH receptor antagonist PMID 11883648
5
Orilanolimab 2066544
(3R,9Z,12Z,15Z,18Z,21Z)
Aqp7 Rat Pre
Deficiency of TOP1MT enhances glycolysis through the stimulation of PDK4 expression in gastric cancer PMID 38200513
MCE
Bethanechol 674
15
Identification and preclinical evaluation of the small molecule, NSC745887, for treating glioblastomas via suppressing DcR3
osmolytem
Antiviral Activity of Peptide
Creg1 Mouse Pre
Production of recombinant choline oxidase and its application in betaine production PMID 34471592
Structural and immunological characterization of E. coli derived recombinant CRM197 protein used as carrier in conjugate vaccines PMID 29875175
Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide PMID 8573568
GSK 625433 885264
Pdcd10 Mouse Pre
Diphtheria PMID 31553838
Choline oxidase 9028
Diphtheria toxin CRM197 92092
二氢辣椒素
Sncg Mouse Pre
Mutatoxanthin 31661
SDCBP Human Pre
TBCB Human Pre
Aminopyridine 2 2411643
7
IL17RD
S16317
Cdc7
FSD1 Human Pre
NPVF Human Pre
Functional Analysis and Clinical Significance of Chloride Channel 2 Expression in Esophageal Squamous Cell Carcinoma PMID 33565032
GT
NecroX7
M 14659 114627
NAAA Human Pre
Microbial production of human milk oligosaccharide lactodifucotetraose PMID 33812022
Slc7a7 Mouse Pre
DEFA4 Human Pre
CLK1/4
PIE 2
KCP Human Pre
Citalopram impurity 2 62498
Estrogen
BAY
Dactylfungin B 146935
MHJ 627
PARP10
PDE4A1A
MBX3135 1636878
Radiation therapy
BC
Trabikibart 2643974
Phosphonate
Creatinine deiminase 37289
PPCS Human Pre
EPB41 Human Pre
COA1 Human Pre
Structure
Hcrtr2 Mouse Pre
AR 201
Artn Mouse Pre
SHF Human Pre
Telmisartan impurity 5 114772
MK0626
7
Selenom Mouse Pre
Pepstanone A
PD
PCN
AMG
IRMOF 3
RHCE Human Pre
ADCK2 Human Pre
IQCD Human Pre
Pigf
Parathyroid hormone
Piperaquine phosphate 85547
Atp2b4
MANF
Phytodegradation
Structure
Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes PMID 11897593
D
Tuftsin
Binding of 2,6
HY
Elipunercept 3037408
Targeting Viral cccDNA for Cure of Chronic Hepatitis B PMID 36034467
PTS 蛋白, Human (His)
PCI 45227
2
MCE
KANSL2 Human Pre
Anti
Carpro
Chondroitinase ABC 蛋白, P. vulgaris (His)
Suacron
Design, synthesis, and biological evaluation of 3
Bradykinin triacetate 5979
Studies of the kinetics of the isolated mitochondrial ATPase using dinitrophenol as a probe PMID 6453612
skin‐lightening agent
Nicergoline 27848
ML267 1542213
CD30 Ligand/TNFSF8 蛋白, Rat (HEK293)
Fungicidal spectrum and biological properties of a new fungicide, pyriofenone PMID 37361489
Pityrogrammin 55601
Lycoperodine
FR
INTS11 Human Pre
Q134R Small chemical compound with NFAT inhibitory properties improves behavioral performance and synapse function in mouse models of amyloid pathology PMID 34117818
1
Boc
AA
Clindamycin phosphate impurity 8 620181
KANK3 Human Pre
BPGM 蛋白, Human (His)
Slc5a7 Mouse Pre
GUK1 activation is a metabolic liability in lung cancer PMID 39919745
KRT10 Human Pre
XR8
TPR
PEG
DDR1
NPAS2 Human Pre
CAG Trimer phosphoramidite
MRM2 Human Pre
RP
(3Z,6Z)
PF 04254644 959584
Aco2 Rat Pre
SAR
Itga3 Mouse Pre
Dimethylhydroxyfuranone
Biotin
CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant PMID 21575866
Famotidine dimer
Aff3 Rat Pre
NNRT
The activity of platelet activating factor
hsa
8
Discovery and optimization of phenazopyridine hydrochloride as novel SARS
CVS995
Asp106
Slc4a7 Mouse Pre
HSMO 9
LRRN3 Human Pre
MSL3 Human Pre
N
(Rac)
NOD2 Human Pre
P2X4
JAK抑制剂、激动剂、拮抗剂、激活剂、调节剂、降解剂、 Control、 Substrate、 Ligand、基因
CHRM2 Human Pre
Aspn Rat Pre
Alpg Rat Pre
Hibch Mouse Pre
overactive bladder symptoms
Flrt2
Kat7
Benzyl 2,3,4
Acta1 Mouse Pre
Estrogen Receptor beta 抗体 (YA1892)（Estrogen Receptor beta Antibody (YA1892)）
HSF2 Human Pre
pH
In vivo antiviral properties of biologically active compounds. II. Studies with influenza and vaccinia viruses PMID 5694419
NBD
Dihydrodiol
Soybean oil, epoxidized acrylate
Generation of a poly
Gaa Rat Pre
Identification of the I38T PA Substitution as a Resistance Marker for Next
DCC3014
Bphl Rat Pre
DSPE
A new group of aromatic prenyltransferases in fungi, catalyzing a 2,7
1,6
GDC
Lipf Rat Pre
Scn2b Mouse Pre
Epigenetic targeted therapy of stabilized BAP1 in ASXL1 gain
PTD10 2642231
Alloaromadendrene
BMS
Synthesis and Biological Evaluation of β
α
2
GDC2394
BAP1
Meloxicam sodium 71125
UROIIIS 蛋白, Human (His)
5
The first synthesis of (
CD127 抗体 (YA545)(PBS only)（CD127 Antibody (YA545)(PBS only)）
diterpenes
Calcitriol reduces Newcastle disease virus replication by modulating galectin 3 and pro
Pyran
MCE
L365209
CML
Laromustine 173424
Inhibition of Receptor Protein Tyrosine Phosphatase β/ζ Reduces Alcohol Intake in Rats PMID 32154588
Neu5Ac
DS96432529 2871872
GW3333
CRX
Glarivibart 3033697
BCL2/BAX
A Comprehensive In Vitro Characterization of a New Class of Indole
CLPP 2068
Chemical structures of constituents from the flowers of Osmanthus fragrans var. aurantiacus PMID 25300343
CHO
Aflatoxin Q1
Ecliptasaponin A attenuates renal fibrosis by regulating the extracellular matrix of renal tubular cells PMID 37831322
Streptimidone
(+)
NSC 268497
AChE
Histamine glutarimide 1464897
Deciphering Fatty Acid Synthase Inhibition
TMX
Isolation of mitraphylline from Uncaria tomentosa (Willd. ex Schult.) DC. barks and development of spectrophotometric method for total alkaloids determination in Cat's Claw samples PMID 31769108
OPRX106
Inactive U0126 Analog
GSK2578215A 1285515
UNC8212
BAY
Gαi
GSK2801
PRMT6
Effects of AZD0837, a novel direct thrombin inhibitor, on the electrophysiological properties of the human heart a randomized, double
CCRL2 Human Pre
Triacetonamine monohydrate 10581
Elubrixin 688763
Bucainide
TRC 253
5
IW6463
MTX23
Fluensulfone
18 1 Succinyl PE 111613
PCNA
Melamine induced cognitive impairment associated with oxidative damage in rat's hippocampus PMID 22564861
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain
CP127374
Safety and efficacy of itepekimab in patients with moderate
CH4933468
Methyl chanofruticosinates from leaves of Kopsia flavida Blume PMID 11394866
柳氮磺吡啶
Apogossypolone 886578
Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species‑mediated apoptosis by targeting the electron transport chain PMID 33125107
β
AZ
Effect of combined DNA repair inhibition and G2 checkpoint inhibition on cell cycle progression after DNA damage PMID 16648558
Azaindole 1
MK0773
4
ACH
Ebpl
Structure and mechanism of the phosphotyrosyl phosphatase activator PMID 16916641
Thrombopoietin Receptor 抗体 (YA3994)（Thrombopoietin Receptor Antibody (YA3994)）
Design, synthesis and biological activity of novel triketone herbicides containing natural product fragments PMID 37532319
(Arg)9 TFA 2283335
Muc15 Rat Pre
FB23 2243736
Peptidomimetic blockade of MYB in acute myeloid leukemia PMID 29317678
NADI
Fmoc
AIE
FGFR4
DMT
GYKI
Synthesis, SAR and in vitro therapeutic potentials of thiazolidine
5
DE112
Ro 32
Rbin
DNASE2 Human Pre
Abx MCP
Timing of Novel Drug 1A
ITX 3
Lunasin 496823
SCARB1 Human Pre
Dhx9 Mouse Pre
Hepcidin
Isolation of MEK5 and differential expression of alternatively spliced forms PMID 7499418
Phenanthrenoids from Juncus acutus L., new natural lipopolysaccharide
TMA
The Novel Tubulin
(Rac)
Discovery of Heparin Mimetic, Potent, and Selective Inhibitors of Human Clotting Factor XIIIa PMID 39035933
MARCKS Human Pre
Hibifolin, a Natural Sortase A Inhibitor, Attenuates the Pathogenicity of Staphylococcus aureus and Enhances the Antibacterial Activity of Cefotaxime PMID 35913166
Synergy Potential of Indole Alkaloids and Its Derivative against Drug
Tailoring lipid nanoparticles for T
Anti
UC514321
cpe30
P
Gzmb Mouse Pre
8
Flucycloxuron
Solabegron hydrochloride 451470
1α,25
CGA279202
Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines PMID 31550659
Multi
A novel peroxisome proliferator
Asperfuran 129277
Fisogatinib (Standard)
Cys
Oxypurinol 2465
3
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