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Constituents from the roots of Heracleum rapula Franch PMID 11991190
Identification and optimization of pteridinone Toll
JAK kinase
Benzyl
FHIT 蛋白, Human (His)
MORAb
Use of cefotaxime, a beta
SHP1 and SHP2 inhibition enhances the pro
Novel AU
3,5
5
Soquinolol 61563
Dexmedetomidine 113775
Non
(
Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice PMID 9416907
New triterpenoids from Kadsura heteroclita and their cytotoxic activity PMID 16557460
A novel red clover hydroxycinnamoyl transferase has enzymatic activities consistent with a role in phaselic acid biosynthesis PMID 19525325
The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis PMID 15037214
Acetyl CoA Carboxylase 1 (ACC1) 抗体 (YA646)（Acetyl CoA Carboxylase 1 (ACC1) Antibody (YA646)）
TAS2R14 agonist
Parishin C Attenuates Oxidative Stress and Inflammation in HT22 Hippocampal Neurons and BV2 Microglia Through Nrf2 Signaling Pathway PMID 40806395
PI3K
SK3530
SU
DS
Curcumol From Plant Roots to Cancer Roots PMID 31360103
KIF5B Human Pre
Design and synthesis of novel 5
antagonist
HM71224, a selective Bruton's tyrosine kinase inhibitor, attenuates the development of murine lupus PMID 28950886
Cytotoxic flavaglines and bisamides from Aglaia edulis PMID 17190457
Shizukolidol 90332
NR6A1 蛋白, Human
Turraea robusta Gürke提取物 (Turraea robusta Gürke)
Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3
Bacithrocin B 160433
Injectable immunomodulation
PGC
L
Blockade of T
Novel Strategies To Activate the Dopamine D1 Receptor Recent Advances in Orthosteric Agonism and Positive Allosteric Modulation PMID 30525590
mTOR Ligand、基因
Il25
Laricitrin 3
A Brain
CAY10701 1616967
Usaramine N
The food additive fast green FCF inhibits α
甲基巴豆酰辅酶 A 羧化酶亚基 2（MCCC2）基因
Computation of enzyme
Bis
Transcriptional profiles of the response of methicillin
Enciprazine
[Butalamine hydrochloride. A new vasoactive substance] PMID 823083
Analysis of metabolome changes in the HepG2 cells of apatinib treatment by using the NMR
Potent antifouling resorcylic acid lactones from the gorgonian
(R)
Sodium tanshinone IIA sulfonate and its interactions with human CYP450s PMID 26932161
Anti
Human genetic adaptation related to cellular zinc homeostasis PMID 37747921
CGS 15943
The role of GDF5 in regulating enthesopathy development in the Hyp mouse model of XLH PMID 38836497
Gastrointestinal alcohol dehydrogenase PMID 9529900
Melflufen hydrochloride (Standard)
Activity of bromhexine and ambroxol, semi
BU72 173265
Berberine, a natural plant alkaloid, synergistically sensitizes human liver cancer cells to sorafenib PMID 30015938
Somatostatin and somatostatin analogues pharmacokinetics and pharmacodynamic effects PMID 7911441
Kisspeptin 13
Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer PMID 38904203
SPI1
PKM2 promotes pulmonary fibrosis by stabilizing TGF
Lead Optimization of Positive Allosteric KV7.2/3 Channel Modulators toward Improved Balance of Lipophilicity and Aqueous Solubility PMID 40198203
Crystal structure of phospholipase A2 in complex with 1
The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion PMID 32488095
setd2 knockout zebrafish is viable and fertile differential and developmental stress
Sulforaphane prevents doxorubicin
Remodelin hydrobromide 1622921
GIBH
Synthesis and anticancer potential of novel xanthone derivatives with 3,6
Chronic hydroxychloroquine improves endothelial dysfunction and protects kidney in a mouse model of systemic lupus erythematosus PMID 24842914
Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction PMID 34837851
ITE, a novel endogenous nontoxic aryl hydrocarbon receptor ligand, efficiently suppresses EAU and T
Neuroprotective effect of asiatic acid against spinal cord injury in rats PMID 27153777
L
2
1,3
4,4′,4′′
FV
Store
The central effect of L
5,5'
Enzymes of the mevalonate pathway of isoprenoid biosynthesis PMID 20932952
The biology of thymic stromal lymphopoietin (TSLP) PMID 23433457
Spinal CCL2 pronociceptive action is no longer effective in CCR2 receptor antagonist
Dichlorophenyl
Lysostaphin an antistaphylococcal agent PMID 18607587
PICK1 抗体 (YA1632)（PICK1 Antibody (YA1632)）
Inhibitory action of niflumic acid on noradrenaline
5
FITC
TREM
Synergistic effects of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex PMID 10942849
Butane
Spen Rat Pre
4,4′
MCE
Structure of the nucleosome
LC
A novel method for the measurement of hepatitis C virus infectious titres using the IncuCyte ZOOM and its application to antiviral screening PMID 25796989
Oxygen tank for synergistic hypoxia relief to enhance mitochondria
The regulatory role of the apelin/APJ axis in scarring Identification of upstream and downstream mechanisms PMID 38508477
Aldgamycin G, a new macrolide antibiotic PMID 3818451
MIL
GBP7 Human Pre
RCOR3 Human Pre
Bispecific Antibody
Sertindole a review of its use in schizophrenia PMID 16529528
Development of rapid multistep carbon
MCE
Synthesis and evaluation of anticancer activity of new 9
The lymphoid lineage
Piclamilast inhibits the pro
肾上腺素受体α1A（ADRA1A）基因
EphB1 蛋白, Human (HEK293, His)
Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth PMID 23841915
Metabolism of beclomethasone dipropionate by cytochrome P450 3A enzymes PMID 23512537
The NK1
Targeting SERT promotes tryptophan metabolism mechanisms and implications in colon cancer treatment PMID 34006301
PARP1/NAMPT
Thalidomide
Novel aminopeptidase N (APN/CD13) inhibitors derived from 3
Rapid detection of an ABT
Fasentin 392721
C3ar1
Macrophage Syk
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization PMID 37054771
Pharmacological inhibition of the cGAS
Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration PMID 35298140
Isavuconazole in the treatment of invasive aspergillosis and mucormycosis infections PMID 27330318
Sertraline Alleviates Chronic Prostatitis by Regulating the TRPV1 Channel PMID 38979434
A Potent SOS1 PROTAC Degrader with Synergistic Efficacy in Combination with KRASG12C Inhibitor PMID 38316747
Delineation of the relative antibacterial activity of cefamandole and cefamandole nafate PMID 18988
Reduced store operated calcium entry contributes to autophagy mediated escape of prostate cancer to oxaliplatin treatment PMID 40189057
In vitro and in vivo antibacterial activities of KB
GZ4 68312
Aurora kinase inhibitors based on the imidazo[1,2
Nanomolar concentration of triclocarban increases the vulnerability of rat thymocytes to oxidative stress PMID 23358139
Dose
Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma PMID 31740676
Inhibition of the Sp1/PI3K/AKT signaling pathway exacerbates doxorubicin
Untangling the ErbB signalling network PMID 11252954
Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF
Discovery of Small Molecules and a Druggable Groove That Regulate DNA Binding and Release of the AP
Glypican
Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cells PMID 24210499
Ultrathin Hydrogel Films Toward Breathable Skin
Exploring the Role of DNMT1 in Dental Papilla Cell Fate Specification during Mouse Tooth Germ Development through Integrated Single
KRAS G12C inhibitor 17 2349393
cis,cis
Identification of DNMT1 selective antagonists using a novel scintillation proximity assay PMID 23671287
Hydrolytic properties of a hybrid xylanase and its parents PMID 18688581
The novel nociceptin/orphanin FQ receptor antagonist Trap
The Prostate
FDA
SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer PMID 38507413
Bi
Phillyrin attenuates norepinephrine
The antimicrobial peptide polyphemusin localizes to the cytoplasm of Escherichia coli following treatment PMID 16569873
Chemical Constituents of Supercritical Extracts from Alpinia officinarum and the Feeding Deterrent Activity against Tribolium castaneum PMID 28420198
Aldioxa 5579
VTA1 Human Pre
Arformoterol tartrate 200815
Reprogramming tumor
The chromatin remodeler ERCC6 and the histone chaperone NAP1 are involved in apurinic/apyrimidinic endonuclease
PROTAC BCL6/GSPT1 Degrader
CRBN ligand
A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells PMID 25100239
α
Two novel ent
Chitosan alleviates symptoms of Parkinson's disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood
Epetraborole Is Active against Mycobacterium abscessus PMID 34280020
含 DDRGK 域 1（DDRGK1）基因
Zindotrine 56383
Streptopyridines, volatile pyridine alkaloids produced by Streptomyces sp. FORM5 PMID 24991297
Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune
Targeting DCAF5 suppresses SMARCB1
Cereblon
PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor
Bis
The naringin/carboxymethyl chitosan/sodium hyaluronate/silk fibroin scaffold facilitates the healing of diabetic wounds by restoring the ROS
Tau Peptide (301
Amentoflavone as a dual
Characterization of SB
Cefmetazole sodium 56796
KLF7 regulates super
细胞周期素 L2（CCNL2）基因
Effects of long
miR32
Nafoxidine 1845
Whole
Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA
Isoproturon
Discovery of novel NSAID hybrids as cPLA2/COX
Ac
IL
Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a PMID 28343940
Ald
Discovery of novel, potent, and selective inhibitors of 3
Activity of pefloxacin and thirteen other antimicrobial agents in vitro against isolates from hospital and genitourinary infections PMID 3460983
FAP 蛋白, Human (Biotinylated, HEK293, His)
TNFAIP1 Human Pre
SARS
SEP
BIRICODAR (VX
HHATL Human Pre
GIPR antagonist 2 3105300
Alkylsulfonamide
Picrasidine Q 101219
Azathioprine in dermatology the past, the present, and the future PMID 16908341
1,3
Identification of the antidepressive properties of C1, a specific inhibitor of Skp2, in mice PMID 33416256
Synthesis, pharmacological characterization, and structure
Neuregulins with an Ig
杀伤细胞凝集素样受体 C2（KLRC2）基因
Triamterene inhibits the delayed rectifier potassium current (IK) in guinea pig ventricular myocytes PMID 8187277
Mafoprazine 80428
Circular RNA MGAT1 regulates cell proliferation and apoptosis in hypoxia
Role of K+ channels in N
Physiological role of Acyl coenzyme A synthetase homologs in lipid metabolism in Neurospora crassa PMID 23873861
Ciglitazone, a peroxisome proliferator
Intercellular propagation of extracellular signal
Estrogen Receptor α Regulates Metabolic
GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid
CD200+ cytotoxic T lymphocytes in the tumor microenvironment are crucial for efficacious anti
mTOR Inhibition Promotes Pneumonitis through Inducing Endothelial Contraction and Hyperpermeability PMID 34251297
M335, a novel small
Potential antiviral activity of rhamnocitrin against influenza virus H3N2 by inhibiting cGAS/STING pathway in vitro PMID 39550441
Susceptibility of multidrug
A secreted form of chorismate mutase (Rv1885c) in Mycobacterium bovis BCG contributes to pathogenesis by inhibiting mitochondria
The Screening Research of NF
Differentiated fibrocytes assume a functional mesenchymal phenotype with regenerative potential PMID 31086819
Phosphodiesterase IV inhibition by piclamilast potentiates the cytodifferentiating action of retinoids in myeloid leukemia cells. Cross
GSK878 2417048
VX
IFNL3
VXN Human Pre
AZD3676
Apelin
Dual Roles of Canagliflozin on Cholangiocarcinoma Cell Growth and Enhanced Growth Suppression in Combination with FK866 PMID 39940750
Monochlorobimane (Standard)
Hispidulin 1447
Amphotericin B PMID 15821914
Discovery of 8
Sigma
Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY
Bromodomain
Autophagy blockage and lysosomal dysfunction are involved in diallyl sulfide
Roflumilast prevents lymphotoxin α (TNF
Palmitoylated COX
Mammalian base excision repair the forgotten archangel PMID 23408852
MCE
Syringaresinol protects against diabetic nephropathy by inhibiting pyroptosis via NRF2
Discovery of a First
Borrelidin is an angiogenesis inhibitor; disruption of angiogenic capillary vessels in a rat aorta matrix culture model PMID 9315080
Targeting PknB, an eukaryotic
Extraction, Purification, Structural Characterization, and Antitumor Effects of Water
Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors PMID 31312404
Discovery and pharmacological characterization of a novel series of highly selective inhibitors of cyclin
A High
SPEN Human Pre
Identification of a novel series of potent and selective CCR6 inhibitors as biological probes PMID 30098865
Dose escalation results from a first
Discrepancy in CCL2 and CCR2 expression in white versus grey matter hippocampal lesions of Multiple Sclerosis patients PMID 25149422
ACAT inhibitor pactimibe sulfate (CS
Methylamino
Single
Gentiopicroside inhibits RANKL
Synthesis and Evaluation of 4
Interaction of cephalosporins with penicillin
Methyl 9(Z)
Gamma
TRIM56 Human Pre
WIZ degrader 5
Inhibition of Prostate Cancer Cells by 4,5
Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice PMID 29425148
3
T7 peptide
Berberine produces antidepressant
RVX
ARID1A suppresses R
Pharmacoepidemiologic and in vitro evaluation of potential drug
Epimedin C enhances mitochondrial energy supply by regulating the interaction between MIC25 and UBC in rodent model PMID 40435285
Ductular reaction
microRNA
Population pharmacokinetic analysis of isoniazid, acetylisoniazid, and isonicotinic acid in healthy volunteers PMID 26282412
The discovery of phenylbenzamide derivatives as Grb7
Baicalin mitigates polycystic ovary syndrome‑associated non‑alcoholic fatty liver disease by inhibiting the AR/SREBP1 axis PMID 40937579
DNA PKcs 抗体 (YA957)（DNA PKcs Antibody (YA957)）
O
Inhibitor of apoptosis proteins (IAP) antagonist induces T
eIF2Bβ 抗体 (YA9256)（eIF2Bβ Antibody (YA9256)）
FR167653 attenuates ischemia and reperfusion injury of the rat lung with suppressing p38 mitogen
PAGE1 Human Pre
Platelet
Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents PMID 22160379
Ethylbenzene
Quercetin
MCE
MCE
17(R)
ARID1A prevents squamous cell carcinoma initiation and chemoresistance by antagonizing pRb/E2F1/c
Elevated PINK1/Parkin
MPDC 159262
CXCL13/CXCR5 signaling axis in cancer PMID 31026453
Palivizumab 188039
Cooperative CCL2/CCR2 and HGF/MET signaling enhances breast cancer growth and invasion associated with metabolic reprogramming PMID 40736024
FV
DNA replication is the target for the antibacterial effects of nonsteroidal anti
Discovery of a novel shp2 protein tyrosine phosphatase inhibitor PMID 16717135
Dacarbazine citrate 64038
AZD
Metrazoline 221225
Quantitative analysis of tivantinib in rat plasma using ultra performance liquid chromatography with tandem mass spectrometry PMID 27179187
Anagliptin hydrochloride 1359670
Effect of Tris, MOPS, and phosphate buffers on the hydrolysis of polyethylene terephthalate films by polyester hydrolases PMID 27642555
Novel benzo[1,4]diazepin
HA1/Hemagglutinin 蛋白, H5N1 (ABG81039, HEK293, His)
Kisspeptin
ShK toxin 172450
Identification of cryptic putative IRESs within the ORF encoding the nonstructural proteins of the human rhinovirus 16 genome PMID 34608523
The effects of selected inhibitors on human fetal adrenal steroidogenesis differs under basal and ACTH
Exploring the N
Antitubercular Nitroimidazoles Revisited Synthesis and Activity of the Authentic 3
M2 macrophages
骨形态发生蛋白 7（BMP7）基因
Characterization of new non
2
Discovery and characterization of a substrate selective p38alpha inhibitor PMID 15362850
Inhibition of cerebroside synthesis in the brains of mice treated with L
Potential therapeutics for effort
DFP
B7
Design, Synthesis, and Characterization of Ogerin
Monitoring the Cascade of Monocyte
GSK4112 1216744
WNK1
L
C81
Anecortave desacetate 10184
Mechanistic study of N
Mal
FAU 泛素样和核糖体蛋白 S30 融合（FAU）基因
Cytembena 21739
Tyrphostin AG1478 Inhibits Encephalomyocarditis Virus and Hepatitis C Virus by Targeting Phosphatidylinositol 4
9
Riociguat prevents hyperoxia
1,4
7
ST1936 1210
PKA
Mode of action of a lysostaphin
MCE
Enterokinase, Porcine
Characterization of TAE684 as a potent LRRK2 kinase inhibitor PMID 22335897
Fmoc
Sodium 2
Hexaamminecobalt(III) chloride 10534
氯索洛芬
1,2
AS3MT facilitates NLRP3 inflammasome activation by m6A modification during arsenic
1,2,3,4,5,6
PGC
Furagin 1672
Buddlejasaponin IVb 152580
Fast Green FCF (Food Green 3) inhibits synaptic activity in rat hippocampal interneurons PMID 11803124
Imatinib attenuates cardiac fibrosis by inhibiting platelet
EPZ004777 1338466
Brain
Zanubrutinib 1691249
Retinyl acetate
FD2024
mTOR诱导剂、基因
GLS2 reduces the occurrence of epilepsy by affecting mitophagy function in mouse hippocampal neurons PMID 39404053
Protective effect of PACAP
DAO
Delta opioid receptor agonists are effective for multiple types of headache disorders PMID 30553828
Illuminating insights into protein
Bcl
Models for acne A comprehensive study PMID 30674767
Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting through a Novel Allosteric Mechanism PMID 39316753
Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high
Overexpression of USP35 enhances the protective effect of hUC
Renal vascular responses to renin inhibition with zankiren in men PMID 7697952
Novel anticarcinoembryonic antigen antibody
An Assessment of the Effects of Azodicarbonamide
SEW06622 261349
含 THAP 域 10（THAP10）基因
The effect of COX
ADRB2 inhibition suppresses cancer immune evasion by regulating tumor SOX10
RG 7697
mTOR inhibitor
蛋白激酶 D3（PRKD3）基因
Aurora
BYBC
5
4,4'
2
Periplocymarin protects against myocardial fibrosis induced by β
Mouse Hemoglobin
SCARB1 links cholesterol metabolism
3,5
Chemical inhibition of HSP90 inhibits TNF
5
Study on the role of pyroptosis in bone resorption induced by occlusal trauma with or without periodontitis PMID 35141913
Progranulin
DMTr
Scutellarin
Yohimbine
2,5
HCN
Cu
2
HCN2 modulator
10(E)
6
Hcn2 Rat Pre
DL
IQCE Human Pre
Adra1a Mouse Pre
MCE
hsa
P
HCN2
hsa
DL 017
Reversal of obesity by targeted ablation of adipose tissue PMID 15133506
IKKβ
SHP2E76K
CHA4583 1351121
mmu
Boc
2,5
PNA backbone derivative
hsa
Sema6a
1,4
Small
HPGDS inhibitor 1 1033836
RETN
Retn Mouse Pre
RG 7697
ERK
JHU58
PSCA Human Pre
hsa
mmu
hsa
hsa
2,2
PF
DNA crosslinker 2 dihydrochloride 2761734
GsAF
IKKα
ARQ501
INSP0154
TAUT
Slc6a6 Rat Pre
CLCN5 Human Pre
干扰素 α 和 β 受体亚基 1（IFNAR1）基因
hsa
L
JNK3 inhibitor
H
PZM21 1997387
SLC6A13 Human Pre
Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B
磷酸核糖氨基咪唑羧化酶和磷酸核糖氨基咪唑琥珀酰甲酰胺合酶（PAICS）基因
Phospho
2
Anti
mmu
SLC6A15 Human Pre
Ubiquitously expressed transcript isoform 2 (UXT
p38δ
Glycine
UBE2E2
KRAS
mmu
hsa
(E)
GPX4
mmu
Maleylsulfathiazole
hsa
sodium chloride
Observing Defect Passivation of the Grain Boundary with 2
pelota mRNA 监测和核糖体拯救因子（PELO）基因
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