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WIZ degrader 8 TFA
Adrenergic Receptor
WIZ Human Pre
Di(1H
RWJ 63556 190967
3
3
EMD121974
4,4′
4,4'
catalase
Saintopin, a dual inhibitor of DNA topoisomerases I and II, as a probe for drug
hsa
MCE
Spermidine mediates acetylhypusination of RIPK1 to suppress diabetes onset and progression PMID 39511379
Tamsulosin 106133
Tuaminoheptane sulfate 6411
ERK1/2 inhibitor 8
AChE
hsa
Antitumor agent
Multi
HIV
hsa
mmu
Mid1ip1 Rat Pre
ULK
A Positive Feedback Loop Between CXCL16 and the Inflammatory Factors IL
HLA
1,4
Slc29a1 Mouse Pre
1,1'
4,4'
Tamsulosin hydrochloride 106463
HIV
Studies on the constituents of bark of Parameria laevigata Moldenke PMID 11383605
RP
Pharmacological inhibition of Kv1.3 channel impairs TLR3/4 activation and type I IFN response and confers protection against Listeria monocytogenes infection PMID 35122955
Resorthiomycin
Antifungal agent 158
Targeting the bacterial sliding clamp peptide 46 2756997
DMT
UBE2E2
α
Glyceryl 1
Scaffold modifications to the 4
Hexaammineruthenium(II) chloride 15305
GSK
5
Eda
RET kinase alterations in targeted cancer therapy PMID 35582449
(R)
4
JMJD6
4
Hydroxy Bosentan
2
1,2,4,5
LIV
Melanocortin 1 receptor mediates melanin production by interacting with the BBSome in primary cilia PMID 39621784
SLC6A16 Human Pre
(9Z
HIV
Targeting the NRF2 pathway with linagliptin to inhibit human hepatocellular carcinoma growth PMID 40581165
PD
BRM/BRG1 ATP
2,6
4,4',4''
MCE
SLC29A1 Human Pre
Benzene
17(R)
4
Carbonylation of Runx2 at K176 by 4
Isourolithin A (Iso
TRAIL R1/TNFRSF10A 蛋白, Human (HEK293, hFc)
Tetridamine 17289
Cefpodoxime sodium 82619
Fanetizole
3
Fc fragments
Eftezirleukin alfa
Tetrahydrofuran
Ibrutinib Contributes to Atrial Arrhythmia through the Autophagic Degradation of Connexins by Inhibiting the PI3K
SAR study of celastrol analogs targeting Nur77
SLC10A2 Protein
Pyridazine
Mitochondria
Effects of arginine vasopressin on the transcriptome of prefrontal cortex in autistic rat model PMID 36239083
A simple electrical stimulation cell culture system on the myelination of dorsal root ganglia and Schwann cells PMID 31124698
Self
Discovery of potent myeloid cell leukemia 1 (Mcl
1,4
Bryonolic acid
Parameritannin A
Bis(N,N& 039;
4
Ciclopirox
Solanidiene 26516
PTGFR Human Pre
Mitoquidone (GR
Aspalatone 147249
5
Connarus monocarpus
SRY
ARI3531
SNAP 94847
Cirazoline hydrochloride 40600
NusB
Amisometradine (阿米美啶)
BMY 25282 (BL 6782)
CCG
Antibacterial agent 319
RNAP
Antifungal agent 143
MSACK
HSC
hsa
Angiogenesis inhibitor 4 417719
hsa
3
INSP
Assessment of solvent residues accessibility using three Sulfo
CCC
Design and synthesis of isoform
C144
Boc
Effects of the factor Xa inhibitor rivaroxaban on the differentiation of endothelial progenitor cells PMID 37268884
UNBS3157
Melarsoprol
Cdcp1
Exploratory studies on soluble small molecule CD4 mimics as HIV entry inhibitors PMID 35063895
Leptin and the regulation of body weigh PMID 21460597
MCE
E1A 结合蛋白 p300（Ep300）基因
溶质载体家族 6 成员 5（Slc6a5）基因
The alpha
1H
4,4',4'',4'''
The potentiation of the coronary dilating and the cardiac action of adenosine or adenine nucleotides by methylhesperidin PMID 5297722
Reversine 656820
IL13RA2 targeted alpha particle therapy against glioblastomas PMID 28562337
Inhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expression PMID 23275491
The Clk2 and Clk3 dual
Hexadecylphosphoserine 133321
Piceatannol selectively inhibited the JNK3 enzyme and augmented apoptosis through inhibition of Bcl
Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion PMID 26165838
Udonitrectag 1458063
[2,2'
HS94 1892594
Apigenin attenuates cisplatin
Heneicosanoic acid sodium 87092
mmu
5,5′
mmu
Fluorescein as an artificial enzyme to mimic peroxidase PMID 27841375
SLC6A8
mTOR
(S)
Dapoxetine
5,10,15,20
Recibokibart 2744274
Purvalanol A induces apoptosis and reverses cisplatin resistance in ovarian cancer PMID 35946506
Metabolism of indole
Tnfrsf13c
Genetically resistant mice lacking interleukin
Neither methionine nor nitrous oxide inactivation of methionine synthase affect the concentration of 5,10
Tumor
Tamsulosin
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β
4,4',4'',4'''
The isolation of stepharine and coclaurine from Sarcopetalum harveyanum PMID 5037484
PF
Nicotinamide 2
SHP2 inhibitor PHPS1 protects against atherosclerosis by inhibiting smooth muscle cell proliferation PMID 29703160
Discovery of [5
ZHX2 Human Pre
Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses PMID 23170896
S 38093 hydrochloride 1222097
Firing frequency and entrainment maintained in primary auditory neurons in the presence of combined BDNF and NT3 PMID 27335179
Selective and synergistic activity of L
CAMKI alpha/CAMK1 蛋白, Human (Active, HEK293, His)
Integration of Transcriptomic and Metabolomic Data to Compare the Hepatotoxicity of Neonatal and Adult Mice Exposed to Aristolochic Acid I PMID 35401701
Differential effects of the putative GBF1 inhibitors Golgicide A and AG1478 on enterovirus replication PMID 20504936
NUDT2 蛋白, Human (His)
3’
Maridomycin, a new macrolide antibiotic. 3. In vitro and in vivo antibacterial activity PMID 4782049
无名指蛋白 170（RNF170）基因
TRPC5 Promotes Intermittent Hypoxia
Drug solubility in biorelevant media in the context of an inhalation
Enteropooling in piglets induced by soya
1,1'
Adipoq
Sct Mouse Pre
Activation of the human c
β
Identification of Better Pharmacokinetic Benzothiazinone Derivatives as New Antitubercular Agents PMID 28626525
USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities PMID 37030295
The natural product CCR5 antagonist anibamine and its analogs as anti
Forward planning for disaster
Development of the First Low Nanomolar Liver Receptor Homolog
Effect of dimephosphon on functional recovery of damaged spinal cord PMID 16984091
CXCL6 (granulocyte chemotactic protein
The novel prostaglandin I2 mimetic ONO
mGlu7 potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome PMID 28814546
Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemia PMID 41271691
Anti
E6130, a Novel CX3C Chemokine Receptor 1 (CX3CR1) Modulator, Attenuates Mucosal Inflammation and Reduces CX3CR1+ Leukocyte Trafficking in Mice with Colitis PMID 28842393
Gut
Germacrane Sesquiterpenoids as a New Type of Anticardiac Fibrosis Agent Targeting Transforming Growth Factor β Type I Receptor PMID 31408333
Comprehensive review on betulin as a potent anticancer agent PMID 25866796
EP009 1462951
Novel Thiazole
Endoplasmic reticulum stress contributes to the cell death induced by UCH
Mitochondrial outer membrane integrity regulates a ubiquitin
Comparison of technetium
Isolation and Identification of Three γ
Ring finger protein 10 improves pirarubicin
Excitation
Tracing Gene Expression Through Detection of β
KIF20A regulates porcine oocyte maturation and early embryo development PMID 25036038
NBQX mediates ventricular fibrillation susceptibility in rat models of anxiety via the Nrf2/HO
Melanotan
Glucose derived carbon nanosphere (CSP) conjugated TTK21, an activator of the histone acetyltransferases CBP/p300, ameliorates amyloid
Novel (2,6
Ursolic acid acetate and iso
Cytotoxic triterpenes from the aerial roots of Ficus microcarpa PMID 15694457
Bcor
(S)
Cytotoxicity of cinchona alkaloid organocatalysts against MES
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 PMID 30422115
Arg
Modified citrus pectin inhibits breast cancer development in mice by targeting tumor
IFN
Rocuronium Bromide 119302
Effect of LSKL peptide on thrombospondin 1
In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities PMID 20810539
Synthesis and biological evaluation of DL
Chloroethylnitrosourea analogue HJ03 overcomes temozolomide resistance of glioblastoma in mice through induction of ferroptosis and apoptosis PMID 41772145
Faropenem medoxomil a treatment option in acute bacterial rhinosinusitis PMID 17181408
1
The Warburg effect and drug resistance PMID 26750865
Lindenane disesquiterpenoids with anti
Etodolac, a cyclooxygenase
Apoptosis induced by atRA in MEPM cells is mediated through activation of caspase and RAR PMID 16291826
CD64 蛋白, Cynomolgus (HEK293, His)
Small
Evaluation of the anti
Docosanoic acid
Chimeric cerebral organoids reveal the essentials of neuronal and astrocytic APOE4 for Alzheimer's tau pathology PMID 35691989
In vitro and in vivo anti
Characterization and proteolytic activity of a cathepsin L
PBN protects NP cells from AAPH
Gastric mucosal CD8+TRM cells are recruited through CXCR5
Induction of human cholesterol 7alpha
Effect of the pesticide, deltamethrin, on Ca2+ signaling and apoptosis in OC2 human oral cancer cells PMID 23829777
TNF
Synthesis and biological evaluation of methylpyrimidine
Interactions between p
Protective effects of madecassoside against Doxorubicin induced nephrotoxicity in vivo and in vitro PMID 26658818
Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury PMID 23184389
Blockade of CXCL10 protects mice from acute colitis and enhances crypt cell survival PMID 12555665
Coumarins and antiplatelet aggregation constituents from Formosan Peucedanum japonicum PMID 8821432
Elafin is a biomarker of graft
ERCC1
Tyrosinase
CABS 161308
Tnfrsf13c
Dispersed Graphene Nanosheets Enhance Piezoelectricity of Poly (L
Bacopaside IV 155545
Generation and characterization of ixekizumab, a humanized monoclonal antibody that neutralizes interleukin
L
MCE
Perphenazine Attenuates the Pro
Sn(iv) meso
Inhibition of MLL1
Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα PMID 34857752
Identification of β
Inhibition of dynamin by dynole 34
NPI52
The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS
2
A Novel Functional Method of Protector Screening for Zebrafish Lateral Line Hair Cells via the Acoustic Escape Response PMID 40329138
Bile acids mediate fructose
SDF
UNC119B Human Pre
Determination of xanthones and flavonoids of methanol extracts obtained from different parts of the plants of three Gentianaceae species PMID 30216794
Toll
ZBTB16 Human Pre
Monoamine Oxidase B inhibitor 5 2969160
DC
Structural and interaction analysis of glycoprotein VI
Bioassay
Identification of Substituted 4
Tri(pyridin
膜片钳技术
Nphs1 Mouse Pre
Rubicon/Baron 抗体 (YA6755)（Rubicon/Baron Antibody (YA6755)）
七亚甲基二溴
Modulating Molecular Chaperones Improves Mitochondrial Bioenergetics and Decreases the Inflammatory Transcriptome in Diabetic Sensory Neurons PMID 26161583
Galectin
Gut
2
(E/Z)
Alisol B 23
Azido
[Usefulness of fenspiride in the treatment of acute otitis media in children] PMID 16124370
RH
Temperature
STK32C Human Pre
Pharmacologic Suppression of B7
Coniferaldehyde inhibits LPS
Loss of NF1 in Melanoma Confers Sensitivity to SYK Kinase Inhibition PMID 36409827
Tissue inhibitor of metalloproteinase
Long noncoding RNA KCNQ1OT1 promotes proliferation and epithelial‑mesenchymal transition by regulation of SMAD4 expression in lens epithelial cells PMID 29749509
Novel ester and acid derivatives of the 1,5
Zbtb16 Rat Pre
Phospho
BTLA/CD272 蛋白, Rhesus Macaque (HEK293, His)
The N
Asparanin A 84633
Cinitapride
Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring PMID 15930441
Structural basis of PPARγ
Thrombospondin
Genomic alterations underlie a pan
Anti
Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation PMID 27599525
Structure
Senkyunolide A inhibits the progression of osteoarthritis by inhibiting the NLRP3 signalling pathway PMID 35225151
Synthesis and in vitro evaluation of biotinylated RG108 a high affinity compound for studying binding interactions with human DNA methyltransferases PMID 16536454
Cellular mechanisms of the cytotoxicity of the anticancer drug elesclomol and its complex with Cu(II) PMID 25550273
Discovery of a peroxisome proliferator activated receptor gamma (PPARgamma) modulator with balanced PPARalpha activity for the treatment of type 2 diabetes and dyslipidemia PMID 19530681
Interferon Receptor Trafficking and Signaling Journey to the Cross Roads PMID 33552080
IGFBP
Verproside inhibits TNF
Timegadine hydrochloride 71080
Ginsenoside Rk1 bioactivity a systematic review PMID 29158964
Real
FCPR03, a novel phosphodiesterase 4 inhibitor, alleviates cerebral ischemia/reperfusion injury through activation of the AKT/GSK3β/ β
Reversal of CRF
Milveterol hydrochloride 804518
MCE
Bafilomycin C1 induces G0/G1 cell
Novel Tree Shrew
'Click' synthesis of a triazole
4,4'
Endothelial microparticles induced by cyclic stretch activate Src and modulate cell apoptosis PMID 32856783
Integrin alpha 5 beta 1 蛋白, Human (HEK293, Flag
Therapeutic potential of recombinant IL
Activity
Distinctive Growth and Transcriptional Changes of the Diatom Seminavis robusta in Response to Quorum Sensing Related Compounds PMID 32582129
LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1 PMID 35398991
Glycosaminoglycan
Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo
The potent melanocortin receptor agonist melanotan
Ndufv2 Rat Pre
Repeated administration of vanilloid receptor TRPV1 antagonists attenuates hyperthermia elicited by TRPV1 blockade PMID 17652633
Pefloxacin and ciprofloxacin increase UVA
Shanzhiside methylester, the principle effective iridoid glycoside from the analgesic herb Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal microglial β
Advances in the discovery of kinesin spindle protein (Eg5) inhibitors as antitumor agents PMID 23434636
Differentiation
Biochemical, structural, and transglutaminase substrate properties of human loricrin, the major epidermal cornified cell envelope protein PMID 7592852
Evidence for the role of neurogenic inflammation components in trypsin
Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson's disease validation of the antiparkinsonian effects of a sigma
Generation of induced neural stem cells with inducible IDH1R132H for analysis of glioma development and drug testing PMID 32946483
ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress
LUC7L2 Human Pre
Engineered extrachromosomal oncogene amplifications promote tumorigenesis PMID 39695225
Identification of MrgX2 as a human G
Helicobacter urease suppresses cytotoxic CD8+ T
Synthesis and biological evaluation of analogues of the potent ADAM8 inhibitor cyclo(RLsKDK) for the treatment of inflammatory diseases and cancer metastasis PMID 27407033
MCE
Progestin and adipoQ receptor 7 (PAQR7) mediate the anti
A histone
New phenylpropanoid allopyranosides from the rhizomes of Cimicifuga dahurica PMID 31126853
mmu
Liptracker
1H
Estrogen metabolism modulates bone density in men PMID 17406768
Ptprn Rat Pre
ATTO 488 iodacetamid 2305285
Antitumor activities of the four sesquiterpene lactones from Elephantopus scaber L PMID 16837899
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation PMID 36704936
2,5
FH535 inhibited metastasis and growth of pancreatic cancer cells PMID 26185454
Utility of human induced pluripotent stem cell
Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use PMID 3884319
DAPK Substrate Peptide 386769
p38 MAPK
Decynium
AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets PMID 27880801
Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist Ned
PtdIns
Liangxue Tongyu prescription attenuates neuroinflammation by increasing cholecystokinin octapeptide in acute intracerebral hemorrhage rats PMID 38941823
Ubiquitin ligase STUB1 destabilizes IFNγ
Versatile Nano
Screening Repurposed Antiviral Small Molecules as Antimycobacterial Compounds by a Lux
Discovery of a New Anti
1,3,5
Gastrointestinal adverse events with sodium polystyrene sulfonate (Kayexalate) use a systematic review PMID 23321430
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2
Single amino acid
Acss2
The PD
Pyronaridine 74847
Synthesis and antitubercular evaluation of 4
Inhibition of para
Lactate Dehydrogenase A 抗体 (YA3482)（Lactate Dehydrogenase A Antibody (YA3482)）
Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus
4
Cyclooxygenase
Galectin
Cizutamig 2919209
A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment PMID 37216120
20 years of DNA Polymerase μ, the polymerase that still surprises PMID 33786971
Octyl gallate An antioxidant demonstrating selective and sensitive fluorescent property PMID 27765226
Azido
Azido
H
β
Mitochondria preserve an autarkic one
Antimicrobial peptide expression in swine granulosa cells in response to lipopolysaccharide PMID 29982140
(D
VGF Human Pre
A new HPLC
GAS6/AXL signaling promotes M2 microglia efferocytosis to alleviate neuroinflammation in sepsis
Three new dammarane glycosides from heat processed ginseng PMID 12214849
CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ PMID 26483204
Ikbke Rat Pre
Two new sesquiterpenes from Sonchus oleraceus and inhibitory mechanism on murine haemangioendothelioma (EOMA) cell lines PMID 34039229
Ptgfr Rat Pre
CPT1C
(4
A New Role for Conivaptan in Ulcerative Colitis in Mice Inhibiting Differentiation of CD4+T Cells into Th1 Cells PMID 34751838
Widespread occurrence of bisphenol A diglycidyl ethers, p
Herkinorin ameliorates neuronal damage in a pentylenetetrazol
Calcium signaling from damaged lysosomes induces cytoprotective stress granules PMID 39533058
Discovery of 1H
Florfenicol
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage PMID 38557489
Uprevstobart 2762201
Cardiovascular effects of NSP
The Difference in Cytotoxic Activity between Two Optical Isomers of Gelsemine from Gelsemium elegans Benth. on PC12 Cells PMID 31130596
PGC1α regulates the mitochondrial metabolism response to cyclic stretch, which inhibits neointimal hyperplasia PMID 40779200
Recombinant trypsin production in high cell density fed
Identification of a stable chemerin analog with potent activity toward ChemR23 PMID 19540290
GW583340 and GW2974, human EGFR and HER
A small molecule modulates circadian rhythms through phosphorylation of the period protein PMID 21954091
Emodin
Telbivudine
USP30 蛋白, Human (sf9, His)
Fraxinol attenuates LPS
IFN
1,1′
In vitro effects of erythromycin and florfenicol on primary cell lines of Unio crassus and Cyprinus carpio PMID 33913106
The E3 ligase VHL controls alveolar macrophage function via metabolic
CNSNQIC (Disulfide bridge Cys1
Characterization of two novel cholecystokinin tetrapeptide (30
Non
Lipid overload impairs hepatic VLDL secretion via oxidative stress
Antineoplastic agents. 595. Structural modifications of betulin and the X
alpha/beta Synuclein 抗体 (YA2999)（alpha/beta Synuclein Antibody (YA2999)）
Cbl
[1,1' 4',1'
DNA 5mC methylation inhibits the formation of G
CI
Quantitative analysis of impurities in leucomycin bulk drugs and tablets A high performance liquid chromatography
Discovery of VU6015929 A Selective Discoidin Domain Receptor 1/2 (DDR1/2) Inhibitor to Explore the Role of DDR1 in Antifibrotic Therapy PMID 31938459
Effects of cinnarizine on calcium and pressure
Inhibition of cancer
Inhibition of spleen tyrosine kinase as treatment of postoperative ileus PMID 23242119
Phenotypic Approaches to Identify Inhibitors of B Cell Activation PMID 25948491
Recombinant osteoprotegerin decreases tumor burden and increases survival in a murine model of multiple myeloma PMID 12543775
Epimers of bicyclo[2.2.2]octan
A genetically encoded biosensor for point
Design, synthesis and biological evaluation of novel 5
Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9
GP6 Human Pre
Exploring the Analgesic Initiation Mechanism of Tuina in the Dorsal Root Ganglion of Minor CCI Rats via the TRPV1/TRPA1
HOCl
Discovery of JND3229 as a New EGFRC797S Mutant Inhibitor with In Vivo Monodrug Efficacy PMID 30429956
Oxidative stress
Anti
Oxymatrine suppresses oral squamous cell carcinoma progression by suppressing CXC chemokine receptor 4 in an m6A modification decrease dependent manner PMID 36004481
MeO
Small Molecule Inhibitor of ATPase Activity of HSP70 as a Broad
Cyclic lactam hybrid α
PCN 777
Identification of 5
Combination therapy of negative pressure wound therapy and antibiotic
TET (Ten
Mesenchymal stem cells ameliorate renal fibrosis by galectin
Synthesis and structure
CEA 抗体 (YA917)（CEA Antibody (YA917)）
Brasofensine maleate 173830
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