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A small molecule inhibitor of p53
FSCPX, a Chemical Widely Used as an Irreversible A₁ Adenosine Receptor Antagonist, Modifies the Effect of NBTI, a Nucleoside Transport Inhibitor, by Reducing the Interstitial Adenosine Level in the Guinea Pig Atrium PMID 30200192
PARP1
Pax6 regulates the formation of the habenular nuclei by controlling the temporospatial expression of Shh in the diencephalon in vertebrates PMID 24528677
844
Azido sphingosine (d18 1)
MK
MG 132
Identification of Co
JS25 2411771
Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model PMID 30763102
Platelet glycoprotein IIb
PVR
Thrombospondin (TSP
3
ALX 5407
SK channels
Enantiodifferentiation through frequency
DC
Discovery of novel tripeptide propylene oxide proteasome inhibitors for the treatment of multiple myeloma PMID 33971487
Substrate specificity characterization of a cdc2
TEI9647
dental
Stearoylcarnitine
Genomic Discovery and Structure
MCE
Pectolinarin Promotes Functional Recovery after Spinal Cord Injury by Regulating Microglia Polarization Through the PI3K/AKT Signaling Pathway PMID 40014266
Transcriptional and epigenetic rewiring by the NUP98 KDM5A fusion oncoprotein directly activates CDK12 PMID 40389480
intestinal barrier.
Efonidipine
Induction of Lung Tumors in Mice with Urethane PMID 26330618
AN
indoxyl
SNU
DENV
Muscarinic M3 positive allosteric modulator ASP8302 enhances bladder contraction and improves voiding dysfunction in rats PMID 35150075
BI689648
U 104
SR 3335
TNIK
RP
NEPP
VX
Selective degradation of splicing factor CAPERα by anticancer sulfonamides PMID 28437394
Four
Development of MBRI
CN009543V 375826
Psoriatic
t
DDO
Fludarabine
ZM253270
photo
SB705498
CM 579
MZH 29
Catalpalactone protects rats nerve function from hypoxic lesion by polarizing microglial cells toward M2 phenotype PMID 39940010
Identification of substituted 5
Discovery of compounds that inhibit SARS
2,6
5
Rutin trihydrate 250249
Discovery of a non
SCT Human Pre
(S)
alpha
Computer
False
SF3B1 抗体 (YA2256)（SF3B1 Antibody (YA2256)）
Aspartic peptidase inhibitors implications in drug development PMID 12749695
FLLL32 1226895
Conformational analysis of prastaglandins. III. Study on active sites and conformation
Cabazitaxel 183133
NELL2 modulates cell proliferation and apoptosis via ERK pathway in the development of benign prostatic hyperplasia PMID 34195782
(S)
TAT 191936
Synthesis and anticancer activities of novel 3,5
Tension of plus
Beaucage reagent
Functional interactions between two Ca2+ channel activators, (S)
4
FSL
Ginkgetin exerts growth inhibitory and apoptotic effects on osteosarcoma cells through inhibition of STAT3 and activation of caspase
Linuron
AAK1
Irisin exerts a therapeutic effect against myocardial infarction via promoting angiogenesis PMID 31061533
Trazodone 19794
Identification of a novel Azaspirooxindolinone
Combining Microfluidic Assessment with Encoded Hydrogel Microparticle
TG (18 0_18 2_20 4) 355807
MCE
激活的 STAT 3 蛋白抑制因子（PIAS3）基因
Design, synthesis, and structure
Amino acid
锥虫二硫化物还原酶
Screening for heat
Castor oil a suitable green source of capping agent for nanoparticle syntheses and facile surface functionalization PMID 30225073
Anti
VPS25 Human Pre
Glial growth is regulated by agonists selective for multiple opioid receptor types in vitro PMID 1665190
Restoration of nigrostriatal dopamine neurons in post
Cerebrovascular characterization of clazosentan, the first nonpeptide endothelin receptor antagonist clinically effective for the treatment of cerebral vasospasm. Part I inhibitory effect on endothelin(A) receptor
MCE
Sappanone A A natural PDE4 inhibitor with dual anti
Antioxidant properties of Thonningianin A, isolated from the African medicinal herb, Thonningia sanguinea PMID 12007576
MW073 3048608
Stinging nettle
The TgAMPK
Design, Synthesis, and Activity Evaluation of Novel Dual
NNZ
mycelium hyperplasia
CB
Assessment of recombinant Lactobacillus vector
Etimicin
Identification of TAK
Lysophosphatidic acid improves oocyte quality during IVM by activating the ERK1/2 pathway in cumulus cells and oocytes PMID 33944929
N
CC 0651
Bederocin
BRL 6231
Laduviglusib monohydrochloride 1797989
ALK5
Aβ40
bioluminescence
biological test
Antiproliferative activity of monastrol in human adenocarcinoma (MCF
ECMO for Cardiac Rescue after Accidental Intravenous Mepivacaine Application PMID 22966472
Efzimfotase alfa 2746354
KRP 197
Syrosingopine
The PKD inhibitor CID755673 enhances cardiac function in diabetic db/db mice PMID 25798941
Cis
SPT5 抗体 (YA2904)（SPT5 Antibody (YA2904)）
BYM338
Pevonedistat Suppresses Pancreatic Cancer Growth via Inactivation of the Neddylation Pathway PMID 35155257
NSC 710464
Vascular cell adhesion molecule 1 expression by biliary epithelium promotes persistence of inflammation by inhibiting effector T
ULK
Laminin peptide CDPGYIGSR 110590
Cefamandole
Parkinson's disease
Thio
Sulfinated proteins
quinolones
SKF96022
LasB
NSC 24068
Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesis PMID 35440095
TNIK
Novel 2
Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion PMID 33144078
OPC 8212
RPMI
LPM
NSC
RAF 265
CD
gamma
Mastoparan7
CGP 37157
D
NADH：泛醌氧化还原酶亚基 A9（NDUFA9）基因
Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites PMID 20044988
Hydra gasdermin
colibactin
nanos C2HC 型锌指 2（NANOS2）基因
Glatiramer Acetate 40 mg/mL in Relapsing
Cyclic GMP
A Concise Enantioselective Synthesis of Fluorinated Pyrazolo
Neuropeptide Y complete amino acid sequence of the brain peptide PMID 6957876
PRT 054021
12 0 EPC
Disc degeneration
Lymphostin
Targeting the lncRNA DUXAP8/miR
Thalidomide
Emerging peptide antibiotics with therapeutic potential PMID 33398258
α
4,4'
Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors PMID 12882839
Lenacapavir 2189684
Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators PMID 27991902
OATD 02
CBP 201
4
Apicidin confers promising therapeutic effect on acute myeloid leukemia cells via increasing QPCT expression PMID 37381175
T 1330
CP 85958
A Preclinical Population Pharmacokinetic Model for Anti
NSC 11779
Blocking of the P2X7 receptor inhibits the activation of the MMP
Synthetic peptides as substrates and inhibitors of a retroviral protease PMID 2837759
U373n
Synergy trap for guardian angels of DNA Unraveling the anticancer potential of phthalazinone
SHMT2 overexpression improves glaucoma by enhancing mitophagy in retinal ganglion cells through promoting the phospho of PINK1 PMID 40604870
Comparison of two experimental thrombosis models in rats effects of four glycosaminoglycans PMID 2549654
Magainin
Preparation of cross
ALK5
Chemical composition and natural durability of juvenile and mature heartwood of Robinia pseudoacacia L PMID 21779654
GRK2i 148505
LNCaP cell
Moscatilin
Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuroinflammation in experimental models of Alzheimer's disease PMID 27926996
Aminoxyacetic acid 645
pro
SCD1 inhibitor
Nitric oxide inhibits interleukin
Butein
Sarglaroids F
MDA19, a novel CB2 agonist, inhibits hepatocellular carcinoma partly through inactivation of AKT signaling pathway PMID 31053086
NNC
MCE
DNA
Dencichin
Protriptyline (N
Anti
The first stereoselective total synthesis of (Z)
Discovery of novel 2,4,5,6
ABI 231
weasels
Acetamiprid
Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II PMID 9079643
Natural products as payloads for antibody
ACG548B
KWD 2183
NSC 721648
Mal
Siremadlin
CDK4/6
Branched
Dense, Continuous Membrane Labeling and Expansion Microscopy Visualization of Ultrastructure in Tissues PMID 38496681
HSP70 attenuates neuronal necroptosis through the HSP90α
Valerian extract and valerenic acid are partial agonists of the 5
Novel Small
Possible involvement of NAMPT in neuronal survival in cerebral ischemic injury under high
Carbaryl
CXCR4 抗体（CXCR4 Antibody）
C.glabrata
QR
RNA
TMX 4113
MS1943 2225938
Differential effect of prostaglandin A1 in hypertensive patients with low, normal and high renin PMID 1077785
Protective effects of marein on high glucose
Dibenzofuran and pyranone metabolites from Hypericum revolutum ssp. revolutum and Hypericum choisianum PMID 19200564
Itolizumab in Psoriasis PMID 28794555
CTR/AMYR agonist
HSF target gene
Interferon
Duloxetine
MKI
Marbofloxacin 115550
DEAD/H
Spermine NONOate 136587
Fenaminosulf
Trypaflavin bromide
rel
H
N
Forkhead box protein FOXK1 disrupts the circadian rhythm to promote breast tumorigenesis in response to insulin resistance PMID 39094826
Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group PMID 11113068
Methyl isonicotinate
Akt signaling is activated by TGFβ2 and impacts tenogenic induction of mesenchymal stem cells PMID 33499914
In vitro effect of dopamine on growth hormone (GH) release from human GH
TRPA1 Contributes to FGFR2c Signaling and to Its Oncogenic Outcomes in Pancreatic Ductal Adenocarcinoma
B7
KLF3 Human Pre
Betiatide
Detection of protein SUMOylation in vivo PMID 19730420
MPO
Src inhibitor dasatinib sensitized gastric cancer cells to cisplatin PMID 36525117
Studies on phosphatidylinositol phosphodiesterase (phospholipase C type) of Bacillus cereus. I. purification, properties and phosphatase
Rational Design of Suprastat A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models PMID 32815366
Flavonoids with antiplasmodial and cytotoxic activities of Macaranga triloba PMID 22561914
4
Roles of NAD(+) / NADH and NADP(+) / NADPH in cell death PMID 19149598
Scots pine (Pinus sylvestris) bark composition and degradation by fungi potential substrate for bioremediation PMID 20005699
Pharmacological rescue of mutant p53 conformation and function PMID 10617466
Blocking transforming growth factor
Mode of action of fluopyram in plant
Astrocytes in preoptic area regulate acute nociception
Immunoregulatory activity of a low
Ordesekimab 879293
Tyr
New antiviral antibiotics, kistamicins A and B. II. Structure determination PMID 8294238
Osteocyte TGFβ1‑Smad2/3 is positively associated with bone turnover parameters in subchondral bone of advanced osteoarthritis PMID 32319543
KS 501 120634
DHA Protects Hepatocytes from Oxidative Injury through GPR120/ERK
SOS1
Effect of cigarette smoking and dietary factors on the amount of N
Residual tembotrione and atrazine in carrot PMID 27052932
In vitro assessment of anticryptosporidial efficacy and cytotoxicity of adenosine analogues using a SYBR Green real
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair PMID 36408828
Disufenton sodium 168021
Lefamulin Review of a Promising Novel Pleuromutilin Antibiotic PMID 30019769
Sphingosine 1
EZH2 negatively regulates PD
TCS 401 243966
Azido
Calenduloside E ameliorates non
MCE
TRPA1 up
Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia PMID 32657463
A Novel Arylurea Fatty Acid That Targets the Mitochondrion and Depletes Cardiolipin To Promote Killing of Breast Cancer Cells PMID 28921987
Avenasterol 23290
Leukotriene C4
3
3′
Mpo
Targeted inhibition of the extracellular signal
Tight junction protein claudin
Structure
Chitosan hydrochloride (80%
Antibiofilm agent
BMS
Structure
Kinetic properties of dual orexin receptor antagonists at OX1R and OX2R orexin receptors PMID 24376396
Reductive Cleavage of Sulfoxide and Sulfone by Two Radical S
NQO2 activator
Oroxylin A regulates glucose metabolism in response to hypoxic stress with the involvement of Hypoxia
P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways PMID 20477948
Appearance and reappearance of mutagens in urine from rats after oral administration of direct brown 95, due to coprophagy PMID 3515634
Creating a multifunctional degrader for co
IL
Discovery of 4
Boc
Implantable system for chronotherapy PMID 34826238
IL
Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660) PMID 28800383
ELL
JNJ
Novel MUC1 aptamer selectively delivers cytotoxic agent to cancer cells in vitro PMID 22384115
Toward a Ferrous Iron
TIGD1
Secondary metabolites of ponderosa lemon (Citrus pyriformis) and their antioxidant, anti
prostate tumor growth
Efficient removal of amoxicillin and paracetamol from aqueous solutions using magnetic activated carbon PMID 28064396
Lactobacillus crispatus 7
A new class of small molecule inhibitor of BMP signaling PMID 23646137
Exendin
Progranulin/PGRN 蛋白, Human (HEK293, His, solution)
(2S,3S)
SIRT1 modulates microglia phenotypes via inhibiting drp1 phosphorylation reduces neuroinflammation in heatstroke PMID 39396713
Increase in the levels of N
High
Pharmacological analysis of Drosophila melanogaster gamma
1,2,3,5
Tiaprofenic acid inhibits the renal reabsorption of sulfate in rats PMID 8361986
Function of ceramide transfer protein for biogenesis and sphingolipid composition of extracellular vesicles PMID 35642450
MCE
Superiority of the Triple
PI3K/mTOR Inhibitor
Overexpression of PRDX4 Modulates Tumor Microenvironment and Promotes Urethane
S 39625 536711
钾钙激活通道亚家族 M 调节 β 亚基 2（KCNMB2）基因
Pyrotinib as a salvage treatment for patients with HER
4
BMS
7
Discovery of Fragment
A potent human anti
(4
Inhibition of acetylcholinesterase by coumarins the case of coumarin 106 PMID 18778776
LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF
Phalloidin 17466
Pumafentrine 207993
Phenethyl acetate
Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ
Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations PMID 31371704
Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate PMID 39667932
Troxerutin suppresses the stemness of osteosarcoma via the CD155/SRC/β
Glatiramer acetate in the treatment of multiple sclerosis emerging concepts regarding its mechanism of action PMID 21476611
TIGIT
Dnttip2 Rat Pre
4
Specific [3H]UK 14,304 binding in human cortex occurs at multiple high affinity states with alpha 2
Butyrylcholinesterase as a biochemical marker PMID 24329513
Dihydrobonducellin 103680
Discovery of a potent, covalent BTK inhibitor for B
Β
A small
PPP2R2B Human Pre
Synthesis and evaluation of novel radioiodinated phenylbenzofuranone derivatives as α
Hydroxymycotrienins A and B, new ansamycin group antibiotics PMID 8682718
Synthesis and structure
Discovery of Novel Pyridazine Herbicides Targeting Phytoene Desaturase with Scaffold Hopping PMID 38781442
Calcium/calmodulin
Regulation of lipid metabolism in grass carp primary hepatocytes by exosomes derived from fatty hepatocytes though GRP78 PMID 39090453
Fish NF
Inhibition of the STIM1/Orai1 Signaling Pathway by Glycine Betaine Mitigates Myocardial Hypertrophy in Spontaneous Hypertension Rats PMID 38187515
Tabimorelin hemifumarate 242143
ZNRF2 抗体 (YA3191)（ZNRF2 Antibody (YA3191)）
TAK1
ZBP1 recognition of beta
α
Identification of potent CNS
Neuropsychopharmacology of JNJ
Zotarolimus alleviates post
Prostaglandin Bx in the prevention of stress ulcers in rats PMID 3835168
Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities PMID 22986292
Effects of glycoprotein IIb/IIIa antagonists on platelet activation development of a transfer method to mimic peak to trough receptor occupancy PMID 12565717
LC
[Tolvaptan (vasopressin receptor antagonist)] PMID 22724238
Cytotoxicity induced by iodinated haloacetamides via ROS accumulation and apoptosis in HepG
The mutant p53
Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN
Benzene
EPHB1 Protein Promoted the Progression of Prostate Adenocarcinoma Through Phosphorylating GSK3B and Activating EPHB1
D
QSAR study of 1,4
PharmGKB summary pathways of acetaminophen metabolism at the therapeutic versus toxic doses PMID 26049587
Combinations of cyclophilin inhibitor NIM811 with hepatitis C Virus NS3
ATMW
Simultaneous Activation of Immunogenic Cell Death and cGAS
Involvement of 5
(R)
KRT81 Human Pre
Methyllycaconitine 21019
A technique for C
Pelopuradazole, a new imidazole derivative alkaloid from the marine bacteria Pelomonas puraquae sp. nov PMID 24597911
Rspo4 Mouse Pre
Zdhhc5 Rat Pre
Split
Comparison of the ocular hypotensive efficacy of eicosanoids and related compounds PMID 6370708
CCW16 2361138
CDK 活化激酶的 MNAT1 成分（MNAT1）基因
LGALS1 Human Pre
Eif5b
2'
KIT (CD117) a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation PMID 16082245
Fructooligosaccharides 308066
Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics PMID 29149605
Cdcp1 Rat Pre
Pharmacological targeting of NLRP3 deubiquitination for treatment of NLRP3
Neurotoxic/neuroprotective activity of haloperidol, risperidone and paliperidone in neuroblastoma cells PMID 21878360
IL
Discovery of a potent and selective JAK1
Phosphatidylethanolamine positively regulates autophagy and longevity PMID 25571976
Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage phagocytosis PMID 37954465
Ginkgetin Alleviates Intervertebral Disc Degeneration by Inhibiting Apoptosis, Inflammation, and Disturbance of Extracellular Matrix Synthesis and Catabolism via Inactivation of NLRP3 Inflammasome PMID 37154418
Effect of the anti
Protective role of long noncoding RNA CRNDE in myocardial tissues from injury caused by sepsis through the microRNA
The relationship of glucokinase activator
Methyl paraben
Chondroitinase B 52227
Isothiazolinone Disrupts Reproductive Endocrinology by Targeting the G
Efficacy and safety of morniflumate for the treatment of symptoms associated with soft tissue inflammation PMID 25921871
CD24 promotes metastasis and chemoresistance by directly targeting Arf6
Resolvin E1 and Inhibition of BLT2 Signaling Attenuate the Inflammatory Response and Improve One
Novel juglone and plumbagin 5
Natural product coumarins that inhibit human carbonic anhydrases PMID 22892213
Agronomic efficiency of NBPT as a urease inhibitor A review PMID 30094079
6
Intrathecal Administration of Flavopiridol Promotes Regeneration in Experimental Model of Spinal Cord Injury PMID 27476919
First evaluation of the safety, pharmacokinetics, and pharmacodynamics of BAY 2433334, a small molecule targeting coagulation factor XIa PMID 34192419
Bintrafusp alfa, a bifunctional fusion protein targeting TGF
Arenobufagin, a bufadienolide compound from toad venom, inhibits VEGF
Discovery and preclinical profiling of 3
ilvB
PROTAC
[Preliminary clinical study on the use of dihexyverine in obstetrics] PMID 13944939
3’,5’
Thymus
5
LanC 样谷胱甘肽 S
AM4299 A and B, novel thiol protease inhibitors PMID 7928694
Regelidine 114542
Efficient methods for isolating five phytochemicals from Gentiana macrophylla using high
Pinaverium impurity 1 54370
MRS 1754 264622
Mepivacaine hydrochloride 1722
PI3'
Nevirapine quinone methide 1061160
Heterologous production of ascofuranone and ilicicolin A in Aspergillus sojae PMID 35418536
Metabolic Regulation of Gene Expression by Histone Lysine β
Cascade Signals of Papaverine Inhibiting LPS
Integrin alpha 5 beta 1 蛋白, Human (HEK293, His)
Pharmacological repression of PPARγ promotes osteogenesis PMID 26068133
Chimmitecan, a novel 9
CDCP1
MCE
Ethyl
Guanadrel 40580
Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108
16(R)
Anti
Preliminary disk diffusion susceptibility testing criteria for cefdaloxime (RU29246, HR
Calpain
Mitophagy Activation Targeting PINK1 Is an Effective Treatment to Inhibit Zika Virus Replication PMID 37300493
Development of activators for SERCA2a for heart failure treatments PMID 41351919
HDAC
Cholesterol depletion activates trafficking
MCE
IPrAuCl 852445
Context
Lactobacillus johnsonii
B Cell Competition for Restricted T Cell Help Suppresses Rare
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