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(2S,4S)
BI
p38 regulates pigmentation via proteasomal degradation of tyrosinase PMID 20053998
Effects of zotepine on extracellular levels of monoamine, GABA and glutamate in rat prefrontal cortex PMID 19371334
卵泡刺激素β亚基（FSHB）基因
3
U0126 protects cells against oxidative stress independent of its function as a MEK inhibitor PMID 25544156
Pgp
HYNIC
Butyrylcholinesterase, cholinergic neurotransmission and the pathology of Alzheimer's disease PMID 15510242
Erythromycin F
2,6
CLR01 sodium
Benzyl DC
Anti
AAK1
MCE
Multidrug resistance protein 1
2,4,6
Cyclobutane
YIAD
Antibiotic SF
CD243
VPC32183 717110
Design of N
Circadian rhythm entrainment with melatonin, melatonin receptor antagonist S22153 or their combination in mice exposed to constant light PMID 15357662
CRBN ligand
Cytosine
Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer PMID 30038258
ABCB1
Effects of zuclomiphene in combination with triparanol and ay
tRNA 甲基转移酶 61B（TRMT61B）基因
Glabridin
Steroids from the roots of Asparagus officinalis and their cytotoxic activity PMID 18713412
The sigma receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia PMID 7498313
Annexin A1 protects epidermal stem cells against ultraviolet
Inhibition of phosphorylated Ser473
锌指和同源盒 2（Zhx2）基因
Anti
Erinacine P 291532
Measurement and modeling of nitric oxide release rates for nitric oxide donors PMID 9114977
Development of Orally Bioavailable Octahydroindole
Relevance of oxidative stress in inhibition of eIF2 alpha phosphorylation and stress granules formation during Usutu virus infection PMID 33493202
Regulation of the severity of neuroinflammation and demyelination by TLR
symplekin 支架蛋白（SYMPK）基因
RIPK1 Promotes Energy Sensing by the mTORC1 Pathway PMID 33271062
Protection of rat heart from ischaemia
1,N6
SGP8 855790
Flumethasone induction of liver tyrosine aminotransferase activity in inbred strains and obese mutant mice PMID 4398019
Rapirosiran 2755196
Irloxacin (Standard)
Ginger metabolites and metabolite
Discovery of THB Derivates as Ferroptosis Inhibitors for the Treatment of Acute Kidney Injury by Targeting VDAC PMID 40402184
Synthesis and biological evaluation of C
Anticancer agent 15 2710312
Aurora kinase
Carboxypeptidase U (CPU, carboxypeptidase B2, activated thrombin
Recognition of RNA N6
3Beta
ZINC000081009201 1424500
Integrin
Octadecyl Rhodamine B perchlorate 142179
Blocking characteristics of hKv1.5 and hKv4.3/hKChIP2.2 after administration of the novel antiarrhythmic compound AZD7009 PMID 15965349
BRCC3 aggravates pulpitis by activating the NF
PKA
Cardol triene 79473
Activities of pefloxacin and ciprofloxacin against experimental malaria in mice PMID 1708223
Empagliflozin Preserves Cardiomyocyte Structural Homeostasis via the Stabilization of the Integrin α5
Studies on the mechanism of action of the gastric microsomal (H+ + K+)
Azido
Octanophenone 1674
Necrotic renal epithelial cell inhibits renal interstitial fibroblast activation role of protein tyrosine phosphatase 1B PMID 23283996
Trolamine salicylate ester 10377
DG051 929915
Isoprocarb
Blarcamesine hydrochloride 195615
Urinary metabolites as biomarkers of human exposure to atrazine atrazine mercapturate in agricultural workers PMID 22155356
ALDH1A
Novel Rho/MRTF/SRF inhibitors block matrix
4'
AN
MCE
Azilsartan 147403
Characterization of the Menin
PLLA4000
CPS2 2756741
Sappanone a prevents diabetic kidney disease by inhibiting kidney inflammation and fibrosis via the NF
CRBN ligand
5
Lycopodium clavatum exine microcapsules enable safe oral delivery of 3,4
HUVEC
Complement factor D 37213
Heat shock factor 1, an inhibitor of non
Changpu Yujin Tang mitigates tourette syndrome by enhancing mitophagy and suppressing NLRP3 inflammasome
(
LncRNA NKILA relieves astrocyte inflammation and neuronal oxidative stress after cerebral ischemia/reperfusion by inhibiting the NF
Melastoma dodecandrum polysaccharide alleviates allergic rhinitis in mice through modulating NLRP3 and IL
IRE1α determines ferroptosis sensitivity through regulation of glutathione synthesis PMID 38750057
PI4KIIIbeta
Suc
ChemR23
Tos
GNKG168 sodium scrambled negative control
Structural basis of γ
Metabolic profile of mephedrone Identification of nor
ER
Rationally Modified Antimicrobial Peptides from the N
Naltiazem hydrochloride 108383
Cdyl2
c
Puquitinib 916890
Menin
Hericenone C 137592
Tri
Mechanism of biochemical action of substituted 4
Pharmacokinetics and UPLC
Determination of Bortezomib in API Samples Using HPLC Assessment of Enantiomeric and Diastereomeric Impurities PMID 28369337
SMARCA2
Asperosaponin VI protects cardiac myocytes from hypoxia
SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cells PMID 24606918
Delmopinol hydrochloride 98092
JNJ
Posaconazole
Taselisib (GDC
EAD1 TFA 2320427
Integrative analysis reveals novel associations between DNA methylation and the serum metabolome of adolescents with type 2 diabetes A cross
Loureirin B 119425
Determination of 3
FZD5
Total synthesis of cordatanine, structural reassignment of drymaritin, and anti
ARD
Effect of oxitropium bromide on histamine
Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator Riociguat in Healthy Young Chinese Male Non
3
SA57 1346169
Selective estrogen receptor
sEH inhibitor
Glaucogenin C mono
D77, one benzoic acid derivative, functions as a novel anti
HDAC5 deacetylates cytosolic ACTN4 during skin reepithelialization and represents a therapeutic target for chronic wound healing PMID 41442502
Discovery of a novel class of selective non
Investigation of Antiplasmodial Effects of Terpenoid Compounds Isolated from Myrrh PMID 32365391
Complement factor H spatial and temporal expression and localization in the eye PMID 16936129
Kinetensin 103131
Structure of D
Effect of electroacupuncture on the cervicospinal P2X7 receptor/fractalkine/CX3CR1 signaling pathway in a rat neck
PTP1B and α
Arenobufagin Promoted Oxidative Stress
Conformationally Restricted Grp94
孕激素和 adipoQ 受体家族成员 7（PAQR7）基因
sPLA2
A multi
Study on dual
Topoisomerase inhibitor 6 2987726
BMS
Phthalimidinoglutarimide
R 56865 104606
3
Fructooligosaccharides From Breast Milk Components to Potential Supplements. A Systematic Review PMID 34555852
eCF309 2001571
Nephroprotective Effects of Cardamonin on Renal Ischemia Reperfusion Injury/UUO
Deucravacitinib 1609392
Darbinurad
Erythromycin, retapamulin, pyridoxine, folic acid, and ivermectin inhibit cytopathic effect, papain
Nanangenines drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis PMID 31807198
ACT
Discovery of a novel olefin derivative as a highly potent and selective acetyl
CDK1
L
PD
(S,R)
NGR peptide 651328
221S
Melittin 20449
2
Targeting dihydroceramide desaturase 1 (Des1) Syntheses of ceramide analogues with a rigid scaffold, inhibitory assays, and AlphaFold2
Discovery of Novel Inhibitors for WD Repeat
Fosquidone 114517
UiO
Romosozumab A Review in Postmenopausal Osteoporosis PMID 32909197
PRE
Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines PMID 22267123
Ainuovirine 1097628
XL44 2637949
Dual Targeting of Apoptotic and Signaling Pathways in T
Effect of oxitropium bromide (Ba253) on increased airway resistance induced by various agonists and antigen in the guinea pig PMID 2528646
RNA sequencing identifies novel regulated IRE1
8
KAHA ligation as a platform for the rapid discovery of Protein Tyrosine phosphatase 1B (PTP1B) inhibitors PMID 39673878
DTE 6892
MiR
Endoplasmic reticulum chaperone GRP78 participates in fluoride
Isolation, identification, and synthesis of two oxidative degradation products of olanzapine (LY170053) in solid oral formulations PMID 17879984
1,4
TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats PMID 20205719
P7C3
Effect of TYB
WY
Evaluation of the neuropharmacological effects of Gardenin A in mice PMID 32181517
Mechanistic and structural insights into the in vitro inhibitory action of hypericin on glutathione reductase purified from baker's yeast PMID 29660796
2,6
Alpha
Discovery and characterization of an inhibitor of glucosylceramide synthase PMID 22497444
Injected hyaluronidase reduces restylane
OF
Effector kinase coupling enables high
Tabirafusp alfa 2839527
Xymedon 14716
A homogeneous high
Fibroblast Growth Factor 9 Suppresses Striatal Cell Death Dominantly Through ERK Signaling in Huntington's Disease PMID 30021209
SGE
Oxidative High Mobility Group Box
Azido
Sphingosylphosphorylcholine alleviates hypoxia
Arborine 6873
Potentiation of Muscarinic M3 Receptor Activation through a New Allosteric Site with a Novel Positive Allosteric Modulator ASP8302 PMID 34244231
AT791 1219962
Hit to lead optimization of the 4
IDOR
Natural Molecules and Neuroprotection Kynurenic Acid, Pantethine and α
PC
Anti
CK1
Nα,Nα
Interruption of RNA processing machinery by a small compound, 1
PI4 Kinase Is a Prophylactic but Not Radical Curative Target in Plasmodium vivax
Synthesis and preliminary behavioural evaluation in mice of new 3
Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats PMID 26254329
Cryptomoscatone D2 276856
Brexpiprazole
Ceftriaxone sodium 958633
Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB
MCE
Nbn Rat Pre
AZ13824374 3040082
UM
MCE
Blidarvetug
MCL
Restoration of cefixime
Dopamine D(3) receptor deletion or blockade attenuates cocaine
Wu
Targeted destruction of VISTA boosts anti
Contractile effect of tachykinins on rabbit small intestine PMID 21441943
GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34
Batzelladine L 956260
Pefloxacin 70458
Ectopic viral integration Site
Hepatoprotective effect of 2'
Syk
Design, synthesis and biological evaluation of novel (E)
MCE
Stimulation of phosphorylation of ERK and CREB by phellopterin and auraptene isolated from Citrusjunos PMID 25522543
Hiding in plain sight Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders PMID 39388906
1
Landiolol, an ultra
Synthesis, antibiofilm activity and molecular docking of N
APC0576, a novel inhibitor of NF
Stimulation of epidermal growth factor receptor threonine 654 phosphorylation by platelet
(4
Mechanism of analgesic action of mesaconitine. I. Relationship between analgesic effect and central monoamines or opiate receptors PMID 6086363
Progerinin, an optimized progerin
2,4
A transgenic reporter under control of an es1 promoter/enhancer marks wound epidermis and apical epithelial cap during tail regeneration in Xenopus laevis tadpole PMID 29291984
IL
Icafolin
The role of renin in the control of the circulation and in hypertensive disease PMID 397605
[2,2'
Dodonaflavonol 1392213
mmp
Formulation and food deprivation affects 2,4
MCE
A First
Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis PMID 37553229
A review of drug isomerism and its significance PMID 23776834
Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in FcεRI
Nematicidal Activity of Kojic Acid Produced by Aspergillus oryzae against Meloidogyne incognita PMID 27197670
Discovery of 4
STYK1 promotes cancer cell proliferation and malignant transformation by activating PI3K
Ptprn Mouse Pre
Final report of the safety assessment of Kojic acid as used in cosmetics PMID 21164073
Macrolides from rare actinomycetes Structures and bioactivities PMID 35041941
Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis PMID 31761722
N,N’,N”
1
Synthetic Site
Isoboldine 3019
Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram
Phosphatase
Methyl succinate 3878
Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2) An Update and Perspective PMID 29847930
Evolution of myeloid
Beyond Antibodies Development of a Novel Protein Scaffold Based on Human Chaperonin 10 PMID 27874025
Itolizumab 1116433
[D
Investigation of the potential pharmacokinetic and pharmaco
angiogenesis
Nootkatone, a neuroprotective agent from Alpiniae Oxyphyllae Fructus, improves cognitive impairment in lipopolysaccharide
Inhibition of c
DTP3 TFA 2759216
(2S,6S)
Cilengitide TFA 199807
Obertamig 2750126
raw
Development of a competitive lateral flow immunoassay for progesterone influence of coating conjugates and buffer components PMID 18791859
DNA
SB 235375
NSC381467 1033006
Topical drug delivery to retinal pigment epithelium with microfluidizer produced small liposomes PMID 24810393
Human complement factor H is a novel diagnostic marker for lung adenocarcinoma PMID 21503575
INCB
PCSK9
Morniflumate 65847
Effect of fomesafen on the embryonic development of zebrafish PMID 32634720
ART0380 2267316
HNF4α antagonists discovered by a high
Cecropin B free acid 203265
Metanephrine 5001
3’
NSC
[(125)I]
Bezeparsen 2639640
BuChE
Discriminative stimulus effects of presynaptic GABA agonists in pentobarbital
GLUTs
Design, synthesis, and activity evaluation of Asiatic acid derivatives as Survivin inhibitors PMID 40414314
Troxipide, a novel antiulcer compound, has inhibitory effects on human neutrophil migration and activation induced by various stimulants PMID 11515628
Docosanoic acid
Toliprolol 2933
Mepivacaine
4
Oxaliplatin Depolarizes the IB4
EPHA10 蛋白, Cynomolgus (HEK293, His)
Dimethylfraxetin 6035
Tolprocarb 911499
Pharmacological characterization and appetite suppressive properties of BMS
Spinosin Inhibits Aβ1
Pacidamycin 7 121808
HER2
Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor
Nafenodone 92615
PDGFRα
Estrogenic and anti
Effects of itaconic acid on neuronal viability and brain mitochondrial functions PMID 34240271
DNP
Serotonin syndrome a brief review PMID 12771076
AGN 193109 sodium 2319838
Converting maslinic acid into an effective inhibitor of acylcholinesterases PMID 26383128
trans
犬尿氨酸酶（KYNU）基因
RBP4 蛋白, Human (HEK293, C
cis
mmu
Gas
CRBN ligand
10(S)
Paeonolide 72520
Evaluation of optimal trophoblastic models to mimic uterine vessel remodeling in human pregnancy† PMID 40358012
FFN200 dihydrochloride 2080306
ELQ
Asic1
carcinoma
Hoe 140 a new potent and long acting bradykinin
Discovery and development of hepatitis C virus NS5A replication complex inhibitors PMID 24621191
Modakafusp alfa 2254522
S 14671 a novel naphthylpiperazine 5
Semax and Pro
BChE
Targeting bromodomains epigenetic readers of lysine acetylation PMID 24751816
Ethyl ferulate, a lipophilic polyphenol, induces HO
Cysteine proteinase inhibitors in murine cysticercosis PMID 16870795
2
Selp Rat Pre
Coumarin
Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex PMID 30726745
H
Gedunin, a limonoid from Xylocarpus granatum, inhibits the growth of CaCo
AST5902 2412155
Aurodox 12704
IWP
N6
Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma PMID 16236844
(meso
HY
Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability PMID 37857143
Disulfo
Metaproterenol hemisulfate 5874
DSPE
In vitro assessment of nystose as a sugar substitute PMID 3295144
Investigations into the Mechanism of Action of Sublancin PMID 30582697
BMS
c
MET kinase
Biochemical characterization of the interactions of the novel pleuromutilin derivative retapamulin with bacterial ribosomes PMID 16940066
Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers PMID 8989005
Modulation of KRAS Mutant by Inhibiting PLK1 Kinase in Cancer Therapeutics PMID 34676025
LL
Preparation and Characterization of Tetrabenazine Enantiomers against Vesicular Monoamine Transporter 2 PMID 20694189
Isolation and characterization of roridin E PMID 27737497
Identification and characterization of SSE15206, a microtubule depolymerizing agent that overcomes multidrug resistance PMID 29459693
The anti
SPP 341498
Cytotoxicity of etidronic acid to human breast cancer cells PMID 18646327
Benzaldehyde is a precursor of phenylpropylamino alkaloids as revealed by targeted metabolic profiling and comparative biochemical analyses in Ephedra spp PMID 22727117
AS
Ligand retargeting by binding site analogy PMID 31077996
tert
Pip5k1c
IL9R Human Pre
Amiodarone toxicity. II. Desethylamiodarone
Photodynamic treatment with purpurin 18 effectively inhibits triple negative breast cancer by inducing cell apoptosis PMID 32623604
Glatiramer acetate 147245
New pacidamycin antibiotics through precursor
C3 Peptide P16 99027
GABA potentiation a logical pharmacological approach for the treatment of acute ischaemic stroke PMID 10854894
MAGEA8 蛋白, Human (His, Strep)
Mecamylamine
Molecular pharmacology of the AMPA agonist, (S)
2
A
Leveraging
Olivetolic acid, a cannabinoid precursor in Cannabis sativa, but not CBGA methyl ester exhibits a modest anticonvulsant effect in a mouse model of Dravet syndrome PMID 34980287
KW
Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del
Immunoproteasome activation expands the MHC class I immunopeptidome, unmasks neoantigens and enhances T
hsa
In vitro risk assessment of AZD9056 perpetrating a transporter
Semisynthetic neoclerodanes as kappa opioid receptor probes PMID 22464684
CLEC12A/MICL 蛋白, Human (HEK293, His)
Talniflumate 66898
Juglone
Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti
A1CF
RBP4 蛋白, Canine (HEK293, His)
Structure
5
Anti
Dazukibart 2639474
MCE
Tovorafenib 1096708
Pinaverium impurity 1 (Standard) (匹维溴铵杂质1 (标准品))
FPTQ 864863
Adriforant hydrochloride 2096455
Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells PMID 34615656
A family of insulin
IND45193 10024
Inosine 5'
Thalidomide
Platelet aggregation unchanged by lipoprotein
Thinking Outside the Box
The novel synthetic triterpenoid, CDDO
Metralindole hydrochloride 53734
AZD7624 1095004
Brasofensine 171655
Methetoin (N3) a trial of a new anti
1
Aromatic interactions with phenylalanine 691 and cysteine 828 a concept for FMS
The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor possible role of M4 receptors PMID 17594079
FLT3
A Dipolar Cycloaddition Reaction To Access 6
PPY
Effects of an oral allosteric AKT inhibitor (MK
3',5'
Asciminib hydrochloride (Standard)
Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment PMID 31652354
Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β
A novel reaction mediated by human aldehyde oxidase amide hydrolysis of GDC
Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models PMID 17893157
FGF10 Human Pre
Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis PMID 35468514
1
MCE
SMND
Quantitation of clonazepam and its major metabolite 7
Tnfrsf13b Rat Pre
成纤维细胞生长因子受体 3（Fgfr3）基因
人乳腺癌抗性蛋白
Dyclonine hydrochloride
SRI
CALD1 Human Pre
IBT6A 1022150
Fmoc
FLI1 Human Pre
Novel Calcium
A
Cysteine dioxygenase 1 attenuates the proliferation via inducing oxidative stress and integrated stress response in gastric cancer cells PMID 36526626
Eseroline a new antinociceptive agent derived from physostigmine with opiate receptor agonist properties. Experimental in vivo and in vitro studies on cats and rodents PMID 7279315
Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists PMID 27926736
Impact of the PD
Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti
Design and Synthesis of Orexin 1 Receptor
LIMD1 Human Pre
Atrazine mercapturate 138722
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