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CRBN ligand
Covalent JAK3 inhibitors based on 2
Induction of endoplasmic reticulum stress and inhibition of colon carcinogenesis by the anti
FKB04
Napyradiomycin C1 103106
Biological impact of freezing Plk1 in its inactive conformation in cancer cells PMID 20139717
Characterization of a novel snake venom component Kazal
Bromoiodoacetic acid
FKB 04
FXYD1 was identified as a hub gene in recurrent miscarriage and involved in decidualization via regulating Na/K
BMVC
FKB
Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells PMID 38438580
Jianpi Huayu Jiedu Decoction prevents the progression of H. pylori and MNU
p62
Ferric carboxymaltose 53858
INT
Ampicillin sodium and Sulbactam sodium (Ampicillin/Sulbactam combination)
Structure
FKBP
Tollip
Optimization of a novel series of N
Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair PMID 18451142
TT
Casein Kinase
A Natural Small Molecule Mitigates Kidney Fibrosis by Targeting Cdc42
[Cell cycle, mitosis and therapeutic applications] PMID 21669563
Preparation and characterization of scutellarin loaded on ultradeformable nano
H
HQ005 2750644
RSPO1 Human Pre
4
Melatonin
MCE
2
CALCB 蛋白, Human (HEK293, hFc)
Paeoniflorin alleviated STZ
Cymoxanil 57966
Vegfc
Development of human calcitonin gene
Thermo
Guanoxyfen nitrate 860385
Moving from Insulin Substitution to the Treatment of the Underlying Autoimmune Disease in Type 1 Diabetes PMID 38688258
In vitro inhibitory effect of EGTA on macrophage adhesion endodontic implications PMID 12669884
(R,S,S)
Sp4 controls constitutive expression of neuronal serine racemase and NF
Id3
Mitochondrial phosphoenolpyruvate carboxykinase 2 counteracts ferroptosis via catalytic activity independent of mitochondrial stress PMID 40712389
NHTD 2540915
Stk32c Mouse Pre
Tumor microenvironment dynamics in oral cancer unveiling the role of inflammatory cytokines in a syngeneic mouse model PMID 39126553
17
Dupilumab improves the molecular signature in skin of patients with moderate
Small molecule inhibitors of the annexin A2 heterotetramer prevent human papillomavirus type 16 infection PMID 25712315
PROTAC EZH2 Degrader
Linezolid PMID 10804037
N3
Effect of NE
Fmoc
α6GABAA receptor positive allosteric modulators targeting trigeminal ganglia for preventing and aborting chronic periorbital allodynia and cephalic pain in both sexes A mechanistic and comparative preclinical study PMID 40652726
Rocastine (AHR
Discovery of a novel A2B adenosine receptor antagonist as a clinical candidate for chronic inflammatory airway diseases PMID 18321039
2
Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer PMID 27557496
前序转位酶相关运动 16（PAM16）基因
MCE
Ethacrynic acid is an inhibitor of human factor XIIIa PMID 35642005
DL
Discovery and mapping of an intracellular antagonist binding site at the chemokine receptor CCR2 PMID 25024169
PC3
HER2
Ba
N
Targeting POH1 inhibits prostate cancer cell growth and enhances the suppressive efficacy of androgen deprivation and docetaxel PMID 31212367
Methyl 4,6
TMEM74 Human Pre
Negative regulation of lymphocyte activation by the adaptor protein LAX PMID 15843560
Novel benzil and isoflavone derivatives from Millettia dielsiana PMID 19140097
9
osteoprotective+agent
New drugs for multiple sclerosis new treatment algorithms PMID 35674067
ODF4 Human Pre
Boc
[Pyrrolizidine alkaloids with chromosome
SELP Human Pre
Antiviral activity of daphnoretin isolated from Wikstroemia indica PMID 19610034
Aard
Implantable Electrical Stimulation at Dorsal Root Ganglions Accelerates Osteoporotic Fracture Healing via Calcitonin Gene
Small molecule nicotinamide N
Assessment of affinity and dissociation ability of a newly synthesized 5
Bis
ICRF
Hepatic uptake and excretion of (
Fmoc
Structure
On the critical role of the substrate the adsorption behaviour of tetrabenzoporphyrins on different metal surfaces PMID 28726947
Novel and established potassium channel openers stimulate hair growth in vitro implications for their modes of action in hair follicles PMID 15816824
Simple isoquinoline and benzylisoquinoline alkaloids as potential antimicrobial, antimalarial, cytotoxic, and anti
PF
Triphenylamines Induce Cell Death Upon 2
Calcitonin gene
4
MCE
Peripheral N
Subunit interaction with PICK and GRIP controls Ca2+ permeability of AMPARs at cerebellar synapses PMID 15895086
The use of electron microscopic immunocytochemistry with silver
TGR5 suppresses high glucose
Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs) PMID 19762238
杀虫素（MLEC）基因
Multiple polymerase acidic (PA) I38X substitutions in influenza A(H1N1)pdm09 virus permit polymerase activity and cause reduced baloxavir inhibition PMID 33351916
Inhibitory effects of kurarinol, kuraridinol, and trifolirhizin from Sophora flavescens on tyrosinase and melanin synthesis PMID 18175961
(S)
6,7
The pattern of histone H3 epigenetic posttranslational modifications is regulated by the VRK1 chromatin kinase PMID 37179361
Selective activity against Mycobacteriumtuberculosis of new quinoxaline 1,4
Anterior insular cortex regulates depression
PLGLAG 726172
Tetradecane
Aerophobin
Carbazole
Catalpol alleviates myocardial ischemia reperfusion injury by activating the Nrf2/HO
Benchmarking AlphaFold
Network
Cholesterol sequestration by nystatin enhances the uptake and activity of endostatin in endothelium via regulating distinct endocytic pathways PMID 21482707
Isolation and cytotoxicity of two new flavonoids from Chrysosplenium grayanum and related flavonols PMID 1955888
TRPC5
Small molecule antagonist of leukocyte function associated antigen
Nrf2
L
Some derivatives of thyroxine PMID 16744161
Urolithin C increases glucose
Pep4c 243843
Discovery and Structure
DA
Diiodoacetic acid 598
ST3 β
Bisbentiamine
Coumarin 343 (C343)
NDC 1308
INDY
Acid black 24
Incorporation of 3
5
A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex
TMP780 (Standard)
血红蛋白亚基δ（HBD）基因
WAY
血红蛋白亚基γ2（HBG2）基因
真核翻译起始因子 5B（EIF5B）基因
Rose oil
Inhbb
Solvent Blue 35
Sergliflozin etabonate 408504
A polysaccharide from Codonopsis pilosula roots attenuates carbon tetrachloride
Pazopanib alleviates neuroinflammation and protects dopaminergic neurons in LPS
IMB5036, a novel pyridazinone compound, inhibits hepatocellular carcinoma growth and metastasis PMID 35020067
Aminooxy
GL
Nonsteroidal anti
Vilagletistat (ZED
Azido
Sortin2
uN2CpolyG
(Rac)
SRT3190 1204707
Beta
Enavatuzumab 1062149
Mal
Discovery of protein arginine methyltransferase 1 inhibitor by structure
跨膜 6 超家族成员 2（TM6SF2）基因
NEK2 promotes the migration and proliferation of ESCC via stabilization of YAP1 by phosphorylation at Thr
CRBN ligand
4
Targeted polypharmacology discovery of dual inhibitors of tyrosine and phosphoinositide kinases PMID 18849971
CID
Sesame oil attenuates Cisplatin
[Anti
含硫氧还蛋白结构域 11（TXNDC11）基因
ICMT
CircHIPK3 regulates cementoblast differentiation via the miR
Integrating Metabolomics, Histopathology, and Cardiac Marker Analysis to Assess Valsartan's Efficacy in Mitigating Dasatinib
Mitochondrial calcium overload contributes to mechanical allodynia in neuropathic pain via inducing mitochondrial dynamic imbalance PMID 40359888
锌指蛋白 436（ZNF436）基因
Dual
VCaP
Epitope
SH
Mechanisms of antiinflammatory action of alpha
Guanine modification of inhibitory oligonucleotides potentiates their suppressive function PMID 23966630
170680
114926
LOX
Ratutrelvir (TRX01)
α
LY
Ammonium bromide (溴化铵)
AVE
Dinitramine (敌乐胺)
Capromab
Monalide (Potablan，庚酰草胺)
Development of MKI
Dehydrate haloperidol
RAF265 (Standard)
CDK9
CGS 15873A
FDH
Effects of antipsychotics and reference monoaminergic ligands on marble burying behavior in mice PMID 18332679
CD44v6 as innovative sarcoma target for CAR
Nat 20(S)
Design, synthesis, and biological evaluation of 1
esterase activity
JNJ
锌指 DHHC 型棕榈酰转移酶 15（ZDHHC15）基因
Translocation Associated Membrane Protein 1 Contributes to Chronic Constriction Injury
Influence of gallate esterification on the activity of procyanidin B2 in androgen
Farabursen sodium scrambled negative control
Fenaminosulf 140
Tubulozole 84697
Tremorine 51
5
Fibulin7 Mediated Pathological Cardiac Remodeling through EGFR Binding and EGFR
ENSA
Glycerophosphocholine phosphodiesterase 9025
A Blood
Mu
Zinc borate 1332
Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut PMID 15337776
SPPHPSPAFSPAFDNLYYWDQ
Guanosine 5'
MST
5
Desmanthin
DUSP18 Human Pre
Discovery of Novel, Potent, and Selective IRAK1 Inhibitors as Potential Therapeutics for Hepatocellular Carcinoma PMID 41637129
Atrogin
LM305
Urban airborne PM2.5 induces pulmonary fibrosis through triggering glycolysis and subsequent modification of histone lactylation in macrophages PMID 38458067
MC
The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice PMID 16647304
ZNRF2
N
Ipsen
Discovery of YYSW001 A Highly Selective, Orally Bioavailable JAK1 Inhibitor Achieving Efficacy under a Moderate
Azido
Azido
Azido
The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53
hematoma
Anti
Ivd Mouse Pre
Environmental Pollutants
Cyclophilin inhibitor 3 1676100
Theasinensin C
GPHA2 Human Pre
Red cell membrane and plasma linoleic acid nitration products synthesis, clinical identification, and quantitation PMID 15273286
cell separation
DISC0280
The Gsh2 homeodomain gene controls multiple aspects of telencephalic development PMID 11060228
HDZI 2,4OH 263153
Erucin, a new promising cancer chemopreventive agent from rocket salads, shows anti
Nidulol 17811
Rab7a
WD 重复域 81（WDR81）基因
Wnt 家族成员 10A（WNT10A）基因
formulation
N10
含 Rieske Fe
Connective tissue growth factor promotes cell
(R)
Anterior gradient 2
Tricaine methanesulfonate 886
Inhibiting mPGES
Inhibition of Smad3 in macrophages promotes Aβ efflux from the brain and thereby ameliorates Alzheimer's pathology PMID 33737172
CLR
Application of chromatography technology in the separation of active alkaloids from Hypecoum leptocarpum and their inhibitory effect on fatty acid synthase PMID 26544947
ALLM
Design, synthesis and evaluation of antioxidant and anti
IL
ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations PMID 31452835
diet type
Bisbentiamine 2667
Rose oil 8007
hsa
(R)
Coumarin 343 55804
C343
Acid black 24 3071
Lehmbachol C 189295
Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation PMID 19109233
Erucin exerts anti
PGD2
A broadly applicable high
Preparation of Tremorine and Gemini Surfactant Precursors with Cationic Ethynyl
Tauroursodeoxycholate 14605
CoRSA
Methylpyrroporphyrin XXI acid 113737
A novel histone acetyltransferase inhibitor modulating Gcn5 network cyclopentylidene
Glu20
Uncovering senescent fibroblast heterogeneity connects DNA damage response to idiopathic pulmonary fibrosis PMID 41394576
polysaccharide polymer
3
Hedgehog signals regulate multiple aspects of gastrointestinal development PMID 10821773
A selective small molecule agonist of the melanocortin
Sonic hedgehog regulates growth and morphogenesis of the tooth PMID 11044393
Computer
HA/Hemagglutinin 蛋白, H1N1 (ALZ46477, HEK293, His)
parasite,
HSP
Combined Cellular Thermometry Reveals That Salmonella typhimurium Warms Macrophages by Inducing a Pyroptosis
CypHer 5 a generic approach for measuring the activation and trafficking of G protein
nonpolyglutamatable antifolate
Characterization of the intestinal absorption of seven flavonoids from the flowers of Trollius chinensis using the Caco
DeDPP4
The dose
聚 (ADP
t
GRK2 mediates cisplatin
myopia
Tellimagrandin II, A Type of Plant Polyphenol Extracted from Trapa bispinosa Inhibits Antibiotic Resistance of Drug
Association between Purpureocillium, amino acid metabolism and cognitive function in drug
ess
ZED 1227
Combretol
Gnetol
149699
Oltipraz metabolite M2
Dusp18 Mouse Pre
FXN 蛋白, Mouse (His)
TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors PMID 29033834
Fuscaxanthone C 15404
Action of the phosphonic analogue of tyrosine and of other tyrosine derivatives on rat liver tyrosine aminotransferase PMID 24190642
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1 PMID 21045145
Gramisterol 1176
Terbutryn
(E/Z)
Astringenin
Coumaran 496
Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer PMID 34616853
COL5A2
8
3338
Lack of cyclic nucleotide regulation of MBCQ
7
ATR
toll 相互作用蛋白（TOLLIP）基因
CRBN ligand
Donanemab 1931944
Anthelmintic Activity and Pathophysiological Effect of Allium sativum Extract
EGFR
Gentulizumab, a novel anti
Calmodulin
Pharmacological and behavioral characterization of D
Calmodulin
A novel miR
CaMK
苯丙氨酰
Autophagy
Propynol Ethoxylate 3973
Cardamonin attenuates cerebral ischemia/reperfusion injury by activating the HIF
non
(S,R,S)
Synergistic cytotoxicity of erianin, a bisbenzyl in the dietetic Chinese herb Dendrobium against breast cancer cells PMID 33385512
Novel Chemical Scaffolds to Inhibit the Neutral Amino Acid Transporter B0AT1 (SLC6A19), a Potential Target to Treat Metabolic Diseases PMID 32180718
NPN12830 22112
Dulcite
Hhip Mouse Pre
Sulfo
Never
Nystatin A2 65086
Transcription Factor YY2 Inhibits Tumor Cell Glutamine Catabolism by Regulating GLS1 RNA Splicing Isoform GAC PMID 40311755
Anti
LY
The action of specific inhibitors of auxin transport on uptake of auxin and binding of N
84102
Discovery of β
Ramatroban 116649
Novel janus kinase 3 inhibitor ritlecitinib suppresses T and B cell responses to prevent acute cardiac allograft rejection in mice PMID 39954912
Terpene Lactucopicrin Limits Macrophage Foam Cell Formation by a Reduction of Lectin
The Economic Contribution of Industry
Mesenchymal stem cells
Expanding the Structural Diversity of Tubulin
Cerulenin 17397
Sequestosome
LCI
SQSTM1
Caspase
Epstein
Discovery of the erianin derivatives as EGFR/tubulin dual
Discovery of High
U0126
heteropolar
AS1604498 361465
In silico, in vitro antioxidant and antihepatotoxic activity of gnetol from Gnetum ula Brongn PMID 31799160
L649923
HLA
VLS1272
Isorhamnetin alleviates cisplatin
COOEt
Tubulozole
Amotosalen hydrochloride 161262
Inhibition of Cathepsin B Ameliorates Murine Cognitive Dysfunction and Neuronal Damage in Ischemic Stroke by Inhibiting Mitochondrial Apoptosis and Drp1
Mosloflavone 740
AC
蛋白磷酸酶 1 调节亚基 16B（PPP1R16B）基因
Dystroglycan from biosynthesis to pathogenesis of human disease PMID 16410545
Profile of blonanserin for the treatment of schizophrenia PMID 23766647
Kaempferol protects mitochondria and alleviates damages against endotheliotoxicity induced by doxorubicin PMID 32145585
Phosphatase activity is dispensable for PRL
Protection from myocardial ischemia/reperfusion injury by a positive allosteric modulator of the A₃ adenosine receptor PMID 22011434
Preventive effects of traditional Chinese medicine formula Huoxiangzhengqi against lipopolysaccharide
MAP2K6 抗体 (YA1088)（MAP2K6 Antibody (YA1088)）
3
(
FGFR2/3
Nicotine effects on cognitive remediation training outcome in people with schizophrenia A pilot study PMID 31437659
Ammelide
AVE
CGS 15873A 118929
Dinitramine induces cardiotoxicity and morphological alterations on zebrafish embryo development PMID 34598048
Ratutrelvir
Kynu Mouse Pre
Human Prostate LNCaP
D
Structure
Ratutrelvir 2929236
LY33169
AVE5997
Rps5 Mouse Pre
TRX01
Nicotine, its metabolism and an overview of its biological effects PMID 15109883
α
Ammonium bromide 12124
An orally available tyrosine kinase ALK and RET dual inhibitor bearing the tetracyclic benzo[b]carbazolone core PMID 27131066
Influence of cetyltrimethyl ammonium bromide on nutrient uptake and cell responses of Chlorella vulgaris PMID 23721850
Discovery of oxazine
Discovery and preclinical antitumor efficacy evaluations of LY32262 and LY33169 PMID 12795528
AVE
TRX
carrots
Dehydrate haloperidol 52669
Human Colon
Development of a 124I
D473
Fmoc
microPET/CT imaging
Molecular Lysine Tweezers Counteract Aberrant Protein Aggregation PMID 31632951
New 20
Cyanine 5 azide 2204261
RBP4
Jun
Neutrophil extracellular traps promote invasion and metastasis via NLRP3
RIP1 kinase inhibitor 1 2095515
A Mitochondria
Cetirizine Impurity B dihydrochloride 1000690
The EARP Complex and Its Interactor EIPR
Ersentilide
TRX 01
saluresis
Azido
L
CBN209350 726201
NAMPT activator 9
Preclinical Pharmacokinetics and Pharmacodynamics and Content Analysis of Gnetol in Foodstuffs PMID 25939395
Oxaloacetate acid ameliorates paraquat
PPP3R1
Design, synthesis and anticancer activity of matrine
Antibiofilm agent
Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics PMID 31034224
The Bisdioxopiperazine ICRF
N19
ACu
Parvifolixanthone B 906794
Biotransformation of mulberroside A from Morus alba results in enhancement of tyrosinase inhibition PMID 20411402
N,N
(±)10(11)
IVD Human Pre
KYNU
BV 2
Azido
KiSS
肌醇三磷酸 3
achaete
Idalopirdine (Lu AE58054)
Pimasertib hydrochloride 1236361
Reliable and Sensitive Detection of Carbonylated Proteins by Oxime Blot PMID 40799477
PNMA 家族成员 3（PNMA3）基因
Benzo[h]quinoline (α
Glidobactin G (滑移菌素 G)
The cationic porphyrin TMPyP4 down
FDX1
Diuretic agents related to indapamide. 1. Synthesis and activity of 1
VU
Endodesmiadiol, a friedelane triterpenoid, and other antiplasmodial compounds from Endodesmia calophylloides PMID 18310952
Swertianolin 23445
3
Re
The cytotoxic activity of ursolic acid derivatives PMID 15922841
ferredoxin 1
Discovery of novel tricyclic full agonists for the G
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